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Determinations of prothrombin time with the semiautomatic fibrometer and with a more automated machine (Electra 600) were compared in regard to reproducibility, accuracy, and speed. Prothrombin times determined for replicate samples with the two machines showed a correlation coefficient of 0.98, but the Electra 600 sensed the clot 0.5 seconds before the fibrometer. The overall coefficients of variation for multiple tests in the normal therapeutic and elevated ranges of prothrombin time were 3.5% for the fibrometer and 2.0% for the Electra 600. The average technician working time was 60% shorter with the fully automated machine than with fibrometer. It is concluded that the automated machine was more accurate and more rapid in determining prothrombin time.
R W Colman, and
G Williams, and
J Wyllie
January 1981,
Annales de biologie clinique,
R W Colman, and
G Williams, and
J Wyllie
August 1973,
Rinsho byori. The Japanese journal of clinical pathology,
R W Colman, and
G Williams, and
J Wyllie
June 1966,
Technical bulletin of the Registry of Medical Technologists. American Society of Clinical Pathologists. Registry of Medical Technologists,
R W Colman, and
G Williams, and
J Wyllie
April 1978,
Research communications in chemical pathology and pharmacology,
R W Colman, and
G Williams, and
J Wyllie
May 1965,
American journal of clinical pathology,
R W Colman, and
G Williams, and
J Wyllie
August 1973,
Canadian journal of medical technology,
R W Colman, and
G Williams, and
J Wyllie
January 1967,
Laboratornoe delo,
R W Colman, and
G Williams, and
J Wyllie
February 1966,
American journal of clinical pathology,
R W Colman, and
G Williams, and
J Wyllie
June 1954,
Geneeskundige gids,
R W Colman, and
G Williams, and
J Wyllie
July 1950,
Wiener Zeitschrift fur innere Medizin und ihre Grenzgebiete,
