Biomaterial Database

Effects of clear topical ointment on transepidermal water loss in jaundiced pretermm infants receiving phototherapy. 2001

S Wananukul, and P Praisuwanna, and K Kesorncam

Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

Thirty jaundiced preterm infants, gestational age < or = 34 weeks and postnatal age < or = 7 days, receiving conventional phototherapy for hyperbilirubinemia of prematurity in incubators were included. 1.5 ml of clear topical ointment was applied on the right side of the trunk and extremities while the left side was used as control. Data collection included transepidermal water loss (TEWL), ambient temperature and ambient humidity, before and at 30 minutes, 4-6 hours after application of the ointment during phototherapy. The measurements were executed both the right and left side in 3 positions; upper arm, back, lower leg. TEWL was reduced by 29 per cent (P value < 0.002) and 26 per cent (P value < 0.011) at 30 minutes and 4-6 hours after the application of clear topical ointment, respectively. Ambient temperature and humidity were not significantly different (P value > 0.18). We concluded that application of clear topical ointment on the skin of jaundiced preterm infants receiving conventional phototherapy in incubators reduced TEWL significantly.

UI	MeSH Term	Description	Entries
D007231	Infant, Newborn	An infant during the first 28 days after birth.	Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D007234	Infant, Premature	A human infant born before 37 weeks of GESTATION.	Neonatal Prematurity,Premature Infants,Preterm Infants,Infant, Preterm,Infants, Premature,Infants, Preterm,Premature Infant,Prematurity, Neonatal,Preterm Infant
D007235	Infant, Premature, Diseases	Diseases that occur in PREMATURE INFANTS.
D007567	Jaundice, Neonatal	Yellow discoloration of the SKIN; MUCOUS MEMBRANE; and SCLERA in the NEWBORN. It is a sign of NEONATAL HYPERBILIRUBINEMIA. Most cases are transient self-limiting (PHYSIOLOGICAL NEONATAL JAUNDICE) occurring in the first week of life, but some can be a sign of pathological disorders, particularly LIVER DISEASES.	Icterus Gravis Neonatorum,Neonatal Jaundice,Physiological Neonatal Jaundice,Severe Jaundice in Neonate,Severe Jaundice in Newborn,Jaundice, Physiological Neonatal,Neonatal Jaundice, Physiological
D009824	Ointments	Semisolid preparations used topically for protective emollient effects or as a vehicle for local administration of medications. Ointment bases are various mixtures of fats, waxes, animal and plant oils and solid and liquid hydrocarbons.	Ointment,Paste,Pastes,Salve,Unguent,Salves,Skin Ointment,Unguents,Ointment, Skin
D010789	Phototherapy	Treatment of disease by exposure to light, especially by variously concentrated light rays or specific wavelengths.	Blue Light Therapy,Blue-light Therapy,Light Therapy,Photoradiation Therapy,Red Light Phototherapy,Therapy, Photoradiation,Blue Light Therapies,Blue-light Therapies,Light Phototherapies, Red,Light Phototherapy, Red,Light Therapies,Light Therapies, Blue,Light Therapy, Blue,Photoradiation Therapies,Phototherapies,Phototherapies, Red Light,Phototherapy, Red Light,Red Light Phototherapies,Therapies, Blue Light,Therapies, Blue-light,Therapies, Light,Therapies, Photoradiation,Therapy, Blue Light,Therapy, Blue-light,Therapy, Light
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012881	Skin Temperature	The TEMPERATURE at the outer surface of the body.	Skin Temperatures,Temperature, Skin,Temperatures, Skin
D014870	Water Loss, Insensible	Loss of water by diffusion through the skin and by evaporation from the respiratory tract.	Insensible Water Loss,Insensible Water Losses