BIOMAT Database Logo BIOMAT Database Logo

Hepatocellular carcinoma: US-guided percutaneous microwave coagulation therapy. 2001

M D Lu, and J W Chen, and X Y Xie, and L Liu, and X Q Huang, and L J Liang, and J F Huang
Department of Hepatobiliary Surgery, First Affiliated Hospital of Sun Yat-sen University of Medical Sciences, 2 Zhongshan Rd, Guangzhou, People's Republic of China. gylumd@public.guangzhou.gd.cn

OBJECTIVE To evaluate the use of percutaneous microwave coagulation therapy for hepatocellular carcinoma, particularly with tumor nodules larger than 2 cm in diameter. METHODS Fifty patients with 107 hepatocellular carcinoma nodules (mean diameter, 2.7 cm +/- 1.5 [SD]; range, 0.8-6.4 cm) were treated with percutaneous microwave coagulation therapy. Single electrode insertion was used in 46 nodules (43.0%) 2 cm or smaller, whereas multiple electrode insertion was applied in 61 (57.0%) nodules larger than 2 cm. RESULTS At 1 month after therapy, technical success for tumors 2 cm or smaller and those larger than 2 cm was achieved in 45 (98%) and 56 (92%) nodules, respectively. After follow-up of 9 months or longer, local recurrence was found in one nodule (2%) sized 1.8 cm and in five nodules (8%) larger than 2 cm. At the end of the study, 26 (52%) of 50 patients were free of disease, and disease-free survival rates at 1 and 2 years were 55% and 41%, respectively. Overall survival rates at 1, 2, and 3 years were 96%, 83%, and 73%, respectively. CONCLUSIONS Percutaneous microwave coagulation therapy is an effective and safe therapeutic modality for hepatocellular carcinoma. A multiple electrode insertion technique can enhance the effectiveness of this therapy in tumors 6 cm or smaller.

UI MeSH Term Description Entries
D008113 Liver Neoplasms Tumors or cancer of the LIVER. Cancer of Liver,Hepatic Cancer,Liver Cancer,Cancer of the Liver,Cancer, Hepatocellular,Hepatic Neoplasms,Hepatocellular Cancer,Neoplasms, Hepatic,Neoplasms, Liver,Cancer, Hepatic,Cancer, Liver,Cancers, Hepatic,Cancers, Hepatocellular,Cancers, Liver,Hepatic Cancers,Hepatic Neoplasm,Hepatocellular Cancers,Liver Cancers,Liver Neoplasm,Neoplasm, Hepatic,Neoplasm, Liver
D008297 Male Males
D008872 Microwaves That portion of the electromagnetic spectrum from the UHF (ultrahigh frequency) radio waves and extending into the INFRARED RAYS frequencies. EHF Waves,Extremely High Frequency Radio Waves,Micro Wave,Micro Waves,Ultrahigh Frequency Waves,Microwave Radiation,EHF Wave,Micro Waves,Microwave,Microwave Radiations,Radiation, Microwave,Ultrahigh Frequency Wave,Wave, EHF,Wave, Micro,Wave, Ultrahigh Frequency,Waves, Micro
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D003972 Diathermy The induction of local hyperthermia by either short radio waves or high-frequency sound waves. Diathermies
D004867 Equipment Design Methods and patterns of fabricating machines and related hardware. Design, Equipment,Device Design,Medical Device Design,Design, Medical Device,Designs, Medical Device,Device Design, Medical,Device Designs, Medical,Medical Device Designs,Design, Device,Designs, Device,Designs, Equipment,Device Designs,Equipment Designs
D005260 Female Females
D005500 Follow-Up Studies Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease. Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D006528 Carcinoma, Hepatocellular A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested. Hepatocellular Carcinoma,Hepatoma,Liver Cancer, Adult,Liver Cell Carcinoma,Liver Cell Carcinoma, Adult,Adult Liver Cancer,Adult Liver Cancers,Cancer, Adult Liver,Cancers, Adult Liver,Carcinoma, Liver Cell,Carcinomas, Hepatocellular,Carcinomas, Liver Cell,Cell Carcinoma, Liver,Cell Carcinomas, Liver,Hepatocellular Carcinomas,Hepatomas,Liver Cancers, Adult,Liver Cell Carcinomas
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

M D Lu, and J W Chen, and X Y Xie, and L Liu, and X Q Huang, and L J Liang, and J F Huang
Ultrasonically guided percutaneous microwave coagulation therapy for small hepatocellular carcinoma.
August 1994, Cancer,
M D Lu, and J W Chen, and X Y Xie, and L Liu, and X Q Huang, and L J Liang, and J F Huang
[Ultrasound-guided percutaneous microwave coagulation therapy for primary hepatocellular carcinoma].
May 2002, Zhonghua zhong liu za zhi [Chinese journal of oncology],
M D Lu, and J W Chen, and X Y Xie, and L Liu, and X Q Huang, and L J Liang, and J F Huang
Percutaneous microwave coagulation therapy for hepatocellular carcinoma.
December 1998, Hiroshima journal of medical sciences,
M D Lu, and J W Chen, and X Y Xie, and L Liu, and X Q Huang, and L J Liang, and J F Huang
[Percutaneous microwave coagulation therapy for hepatocellular carcinoma].
October 1999, Gan to kagaku ryoho. Cancer & chemotherapy,
M D Lu, and J W Chen, and X Y Xie, and L Liu, and X Q Huang, and L J Liang, and J F Huang
Percutaneous microwave coagulation therapy for superficial hepatocellular carcinoma.
January 1999, Hepato-gastroenterology,
M D Lu, and J W Chen, and X Y Xie, and L Liu, and X Q Huang, and L J Liang, and J F Huang
Percutaneous microwave coagulation therapy for unresectable hepatocellular carcinoma.
January 1999, Hepato-gastroenterology,
M D Lu, and J W Chen, and X Y Xie, and L Liu, and X Q Huang, and L J Liang, and J F Huang
Percutaneous sonographically guided microwave coagulation therapy for hepatocellular carcinoma: results in 234 patients.
June 2003, AJR. American journal of roentgenology,
M D Lu, and J W Chen, and X Y Xie, and L Liu, and X Q Huang, and L J Liang, and J F Huang
[Indication of percutaneous microwave coagulation therapy for hepatocellular carcinoma].
October 1999, Gan to kagaku ryoho. Cancer & chemotherapy,
M D Lu, and J W Chen, and X Y Xie, and L Liu, and X Q Huang, and L J Liang, and J F Huang
[Curative effect of percutaneous microwave coagulation therapy for hepatocellular carcinoma].
January 2002, Zhonghua zhong liu za zhi [Chinese journal of oncology],
M D Lu, and J W Chen, and X Y Xie, and L Liu, and X Q Huang, and L J Liang, and J F Huang
[Percutaneous microwave coagulation therapy and endoscopic microwave coagulo-necrotic therapy for small hepatocellular carcinoma].
May 1996, Nihon rinsho. Japanese journal of clinical medicine,
Copied contents to your clipboard!