Biomaterial Database

[Characteristics of urogenital and post-enterocolitis reactive arthritides]. 2001

A L Burmistrova, and A O Isakanova, and A S Prazdnov, and T A Suslova

State University, Medical Academy, Regional Blood Transfusion Station, Chelyabinsk, Russia.

The immune status and profile of HLA antigens of loci A and B were evaluated in 159 patients with reactive arthritis. Reactive arthritis was caused by urogenital chlamydial infection in 64.2% of cases and by Shigella, Salmonella and Yersinia enterocolitica infection in 18.9% of cases. In patients with different etiology of the disease some variations in its course and outcome, immune status as well as in the HLA antigen profile were established that is indicative of genetic determination of the immune response character. The established specific variations in the immune and immunogenetic status of patients with reactive arthritis of different etiology may be used for improving diagnosis and treatment efficacy.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D002690	Chlamydia Infections	Infections with bacteria of the genus CHLAMYDIA.	Infections, Chlamydia,Chlamydia Infection,Infection, Chlamydia
D004760	Enterocolitis	Inflammation of the MUCOSA of both the SMALL INTESTINE and the LARGE INTESTINE. Etiology includes ISCHEMIA, infections, allergic, and immune responses.	Enterocolitides
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D001424	Bacterial Infections	Infections by bacteria, general or unspecified.	Bacterial Disease,Bacterial Infection,Infection, Bacterial,Infections, Bacterial,Bacterial Diseases
D015234	HLA-A Antigens	Polymorphic class I human histocompatibility (HLA) surface antigens present on almost all nucleated cells. At least 20 antigens have been identified which are encoded by the A locus of multiple alleles on chromosome 6. They serve as targets for T-cell cytolytic responses and are involved with acceptance or rejection of tissue/organ grafts.	Antigens, HLA-A,HLA-A,Antigens, HLA A,HLA A Antigens
D015235	HLA-B Antigens	Class I human histocompatibility (HLA) surface antigens encoded by more than 30 detectable alleles on locus B of the HLA complex, the most polymorphic of all the HLA specificities. Several of these antigens (e.g., HLA-B27, -B7, -B8) are strongly associated with predisposition to rheumatoid and other autoimmune disorders. Like other class I HLA determinants, they are involved in the cellular immune reactivity of cytolytic T lymphocytes.	Antigens, HLA-B,HLA-B Antigen,HLA-B,Antigen, HLA-B,Antigens, HLA B,HLA B Antigen,HLA B Antigens
D016918	Arthritis, Reactive	An aseptic, inflammatory arthritis developing secondary to a primary extra-articular infection, most typically of the GASTROINTESTINAL TRACT or UROGENITAL SYSTEM. The initiating trigger pathogens are usually SHIGELLA; SALMONELLA; YERSINIA; CAMPYLOBACTER; or CHLAMYDIA TRACHOMATIS. Reactive arthritis is strongly associated with HLA-B27 ANTIGEN.	Arthritis, Postinfectious,Arthritis, Post-Infectious,Post-Infectious Arthritis,Postinfectious Arthritis,Reactive Arthritis,Reiter Disease,Reiter Syndrome,Reiter's Disease,Reiter's Syndrome,Arthritis, Post Infectious,Post Infectious Arthritis,Post-Infectious Arthritides,Postinfectious Arthritides,Reactive Arthritides,Reiters Disease,Reiters Syndrome