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This is the report of the presence of a benign gastric ulcer in a patient with achlorhydria and documented pernicious anemia. The pernicious anemia was established by a Histalog-fast achlorhydria, a Schilling test of 2.1% excretion of tagges vitamin B12 in a 24-hr urine, and reticulocytosis after administration of cyanocobalamine. Following Histalog (1.5 mg per kg of body weight), the gastric volume was 40 ml, there was no acid, and the pH was 8.1. The ulcer demonstrated by gastroscopy was confirmed at gastrectomy. Histological examination of the ulcer and the remainder of the stomach showed no malignancy. The principal conclusion of this paper is that the patient did not have an acid-produced ulcer, but that bile regurgitation coupled with alcohol ingestion produced the lesion. Surgical investigation of the ulcer seemed mandatory because of the known increased incidence of gastric carcinoma in patients with pernicious anemia.
J W Manier, and
E Beltaos
December 1962,
Proceedings of the staff meetings. Mayo Clinic,
J W Manier, and
E Beltaos
February 1980,
Digestive diseases and sciences,
J W Manier, and
E Beltaos
June 1990,
The Journal of the American Osteopathic Association,
J W Manier, and
E Beltaos
January 1965,
Klinicheskaia khirurgiia,
J W Manier, and
E Beltaos
April 1978,
The Australian and New Zealand journal of surgery,
J W Manier, and
E Beltaos
March 2005,
Digestive diseases and sciences,
J W Manier, and
E Beltaos
September 2002,
Journal of clinical gastroenterology,
J W Manier, and
E Beltaos
November 1967,
Connecticut medicine,
J W Manier, and
E Beltaos
June 1990,
Acta paediatrica Japonica : Overseas edition,
J W Manier, and
E Beltaos
May 1947,
Archives of dermatology and syphilology,
