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Hepatic protein synthesis was measured in vivo and in vitro (liver slice) in 6- and 19-day-old rats. Fed and 15-hour starved rats were compared in each individual experiment. The study demonstrated that in the 6-day-old rat, hepatic protein synthesis is very sensitive to restrictions in dietary influx. In contrast, no significant differences in protein synthesis were detected when 19-day-old rats were fasted for 15 hours. In the fed state, the protein synthetic activity of the tissue unit was the same irrespective of age. Thus, it appears that it is not the maximal capacity for protein synthesis that changes with age, but rather the extent to which the system can adapt to the changing nutritional environment.
E M Vavrousek-Jakuba, and
S A Miller
April 1972,
The Journal of nutrition,
E M Vavrousek-Jakuba, and
S A Miller
February 1979,
The Biochemical journal,
E M Vavrousek-Jakuba, and
S A Miller
December 1988,
Biochimica et biophysica acta,
E M Vavrousek-Jakuba, and
S A Miller
March 1977,
The Journal of surgical research,
E M Vavrousek-Jakuba, and
S A Miller
December 1990,
Biochemical Society transactions,
E M Vavrousek-Jakuba, and
S A Miller
October 1979,
Indian journal of experimental biology,
E M Vavrousek-Jakuba, and
S A Miller
May 1973,
Biochemical and biophysical research communications,
E M Vavrousek-Jakuba, and
S A Miller
May 1974,
Biochimica et biophysica acta,
E M Vavrousek-Jakuba, and
S A Miller
August 1971,
Comparative biochemistry and physiology. A, Comparative physiology,
E M Vavrousek-Jakuba, and
S A Miller
December 1955,
Experimental cell research,
