[Historical review of insulin and its preparations in pharmacopoeia (I) Biological assays] (Jpn).
1990
M Suehiro
UI
MeSH Term
Description
Entries
D007328
Insulin
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
Iletin,Insulin A Chain,Insulin B Chain,Insulin, Regular,Novolin,Sodium Insulin,Soluble Insulin,Chain, Insulin B,Insulin, Sodium,Insulin, Soluble,Regular Insulin
D049711
History, Modern 1601-
The period of history from 1601 of the common era to the present.
History, Modern,Modern History,History of Medicine, Modern,Medicine, Modern,Modern History (Medicine),Modern Medicine,1601- History, Modern,History, Modern (Medicine),History, Modern 1601,Modern 1601- History