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Anterior pituitaries from female Sprague-Dawley rats (160-200 g b.w) bearing electrolytic lesions of the median eminence were qualitatively and quantitatively investigated by electron microscopy and the findings compared with those from intact animals or sham-operated controls. This study was performed in basal conditions and after stimulation with thyrotropin-releasing hormone. Animals with lesions showed a reduction of both the number of somatotrophic cells and growth hormone granules. After injection of thyrotropin-releasing hormone exocytosis of growth hormone granules from somatotrophs was frequent in rats with lesions of the median eminence but rare in sham-operated animals. The differences were statistically significant.
G L Rossi, and
D Probst, and
A E Panerai, and
D Cocchi, and
V Locatelli, and
E E Müller
May 1982,
Endocrinology,
G L Rossi, and
D Probst, and
A E Panerai, and
D Cocchi, and
V Locatelli, and
E E Müller
February 1977,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
G L Rossi, and
D Probst, and
A E Panerai, and
D Cocchi, and
V Locatelli, and
E E Müller
June 1977,
The Journal of clinical endocrinology and metabolism,
G L Rossi, and
D Probst, and
A E Panerai, and
D Cocchi, and
V Locatelli, and
E E Müller
June 1976,
Endocrinology,
G L Rossi, and
D Probst, and
A E Panerai, and
D Cocchi, and
V Locatelli, and
E E Müller
June 1984,
The Journal of pharmacology and experimental therapeutics,
G L Rossi, and
D Probst, and
A E Panerai, and
D Cocchi, and
V Locatelli, and
E E Müller
May 1988,
Neuroendocrinology,
G L Rossi, and
D Probst, and
A E Panerai, and
D Cocchi, and
V Locatelli, and
E E Müller
October 1975,
Endocrinology,
G L Rossi, and
D Probst, and
A E Panerai, and
D Cocchi, and
V Locatelli, and
E E Müller
June 1977,
Endocrinology,
G L Rossi, and
D Probst, and
A E Panerai, and
D Cocchi, and
V Locatelli, and
E E Müller
September 1972,
Endocrinology,
G L Rossi, and
D Probst, and
A E Panerai, and
D Cocchi, and
V Locatelli, and
E E Müller
February 1977,
Cell and tissue research,
