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The clinical course and renal pathology of 17 children with acute extracapillary proliferative glomerulonephritis is reported. Patients with systemic diseases associated with renal involvement were excluded. The onset followed streptococcal infection in ten; of these, four have died, one has been transplanted, and the remaining five have completely healed. The mean follow-up of the latter five patients was 32 months (range, 18 to 57 months). Of the other seven patients without evidence of precedeing streptococcal infection, two have died, two have been transplanted, and the remaining three all have hypertension, proteinuria, and reduced creatinine clearance. The mean follow-up of the latter three patients was 29 months (range, 14 to 38 months). The initial renal histopathologic changes and their progress in later renal biopsies is described. The role of various therapeutic agents is discussed. The prognosis in acute extracapillary proliferative glomerulonephritis following streptococcal infection appears to be better than in ones without preceding streptococcal infection.
S K Anand, and
C W Trygstad, and
H M Sharma, and
J D Northway
January 1997,
Ryoikibetsu shokogun shirizu,
S K Anand, and
C W Trygstad, and
H M Sharma, and
J D Northway
February 1974,
La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris,
S K Anand, and
C W Trygstad, and
H M Sharma, and
J D Northway
November 1988,
Deutsche medizinische Wochenschrift (1946),
S K Anand, and
C W Trygstad, and
H M Sharma, and
J D Northway
January 1972,
Advances in nephrology from the Necker Hospital,
S K Anand, and
C W Trygstad, and
H M Sharma, and
J D Northway
October 1988,
Medicina clinica,
S K Anand, and
C W Trygstad, and
H M Sharma, and
J D Northway
June 1980,
British medical journal,
S K Anand, and
C W Trygstad, and
H M Sharma, and
J D Northway
July 1982,
Polski tygodnik lekarski (Warsaw, Poland : 1960),
S K Anand, and
C W Trygstad, and
H M Sharma, and
J D Northway
June 1987,
Revista clinica espanola,
S K Anand, and
C W Trygstad, and
H M Sharma, and
J D Northway
January 2005,
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia,
S K Anand, and
C W Trygstad, and
H M Sharma, and
J D Northway
May 1986,
Klinicheskaia meditsina,
