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Autologous peripheral blood leukocytes, labeled in vitro with 67Ga citrate, have been studied in 20 patients as a radioactive carrier for the scintigraphic visualization of septic inflammatory areas. 67Ga citrate was added to venous whole blood; following incubation, the blood was centrifugated, and the packed cells were reinfused. Scintiscans were obtained four and 24 hours later. The inflammatory process was demonstrated in nine of nine patients with confirmed sepsis. Eleven patients without sepsis had normal scans. There were no false-negative scans and one-false-positive scan. The selective accumulation of the gallium labeled leukocytes in areas of septic inflammation was sufficient to allow scintigraphic demonstration of the inflammatory area.
R L Burleson, and
B L Holman, and
D E Tow
January 1985,
European journal of nuclear medicine,
R L Burleson, and
B L Holman, and
D E Tow
October 1973,
Annals of surgery,
R L Burleson, and
B L Holman, and
D E Tow
May 1977,
Surgery, gynecology & obstetrics,
R L Burleson, and
B L Holman, and
D E Tow
February 1976,
Nuclear-Medizin,
R L Burleson, and
B L Holman, and
D E Tow
December 1987,
Ugeskrift for laeger,
R L Burleson, and
B L Holman, and
D E Tow
January 1971,
Schweizer Archiv fur Neurologie, Neurochirurgie und Psychiatrie = Archives suisses de neurologie, neurochirurgie et de psychiatrie,
R L Burleson, and
B L Holman, and
D E Tow
July 1989,
Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti,
R L Burleson, and
B L Holman, and
D E Tow
March 1950,
The Journal of clinical investigation,
R L Burleson, and
B L Holman, and
D E Tow
May 1974,
Journal of nuclear medicine : official publication, Society of Nuclear Medicine,
R L Burleson, and
B L Holman, and
D E Tow
July 1979,
AJR. American journal of roentgenology,
