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Inoculation to children of live measles L-16 vaccine was found to cause changes in the content of the main serum classes of immunoglobulins, A, M and G, and synthesis of specific antibody of various physico-chemical nature. Between these two values only a relative correlation was observed at 10--14 and 28--32 days after vaccination. Changes in the synthesis of serum immunoglobulins in the majority of the children were not great and statistically insignificant. Only in 2 children with hypergammaglobulinemia inoculation of measles L-16 vaccine induced intensive (statistically significant) increase in serum M and G globulins. The results indicate the necessity of further study of the effects of live measles vaccine on the immunological status of children which could probably reveal the causes of occurrence of unusual postvaccination reactions and complications.
N T Tikhonova, and
Iu A Prokudina, and
T M Khrometskaia, and
E E Potemkina
January 1990,
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N T Tikhonova, and
Iu A Prokudina, and
T M Khrometskaia, and
E E Potemkina
January 1973,
Voprosy virusologii,
N T Tikhonova, and
Iu A Prokudina, and
T M Khrometskaia, and
E E Potemkina
September 1985,
Pediatriia,
N T Tikhonova, and
Iu A Prokudina, and
T M Khrometskaia, and
E E Potemkina
August 1979,
Klinicheskaia meditsina,
N T Tikhonova, and
Iu A Prokudina, and
T M Khrometskaia, and
E E Potemkina
January 1980,
Antibiotiki,
N T Tikhonova, and
Iu A Prokudina, and
T M Khrometskaia, and
E E Potemkina
April 1971,
Zhurnal mikrobiologii, epidemiologii i immunobiologii,
N T Tikhonova, and
Iu A Prokudina, and
T M Khrometskaia, and
E E Potemkina
January 1987,
Zhurnal mikrobiologii, epidemiologii i immunobiologii,
N T Tikhonova, and
Iu A Prokudina, and
T M Khrometskaia, and
E E Potemkina
July 1980,
Voprosy okhrany materinstva i detstva,
N T Tikhonova, and
Iu A Prokudina, and
T M Khrometskaia, and
E E Potemkina
July 1977,
Problemy gematologii i perelivaniia krovi,
N T Tikhonova, and
Iu A Prokudina, and
T M Khrometskaia, and
E E Potemkina
September 1986,
Vrachebnoe delo,
