By itinerant (zou jie), it refers to the physicians from southern Fujian and Taiwan who possess some special medical characteristics. They are TCM physicians. By chance, this author found a book, Zou Jie Hui Xin Lu, and explored its author and his native place, analyzed the historical background of the appearance of such physicians and their lofty medical morality during the Ming-Qing dynasties. Conclusion has been reached that the so-called itinerant medicine accumulated rich experience, emphasized an overall idea. However, it was also restricted by geographical area and the divorce of theory with practice.