Trigeminal somatosensory evoked potentials in humans. 2001

K Van Loven, and R Jacobs, and J Van Hees, and S Van Huffel, and D van Steenberghe
Laboratory of Oral Physiology, Dept. of Periodontology, Katholieke Universíteit Leuven, Kapucijnenvoer 7, B-3000 Leuven.

The recording of somatosensory evoked potentials (SEPs) is a non-invasive routine clinical testing procedure in neurology. For trigeminal nerve stimulation, however, SEPs have not received a widespread clinical attention. A variety of protocols and procedures have been used to record trigeminal SEPs (TSEPs). Differences encountered include the stimulation mode, site and frequency, the recording electrode position and data acquisition parameters. This has resulted in a diversity of recorded TSEP signals, making comparisons almost impossible. The general picture shows a number of short latency waves (within 3 ms) of peripheral origin, followed by at least two longer latency waves (12-15 ms and 19-22 ms). Furthermore, potential waves with a very long latency (> 100 ms) follow when the response is produced by painful stimulation. The origin of the long and very long latency waves is still a matter of debate. In order to allow reliable data interpretation and comparisons between the outcome of different studies, a standardized protocol should be applied for TSEP recordings. By providing an overview, this paper aims to mark a step forward in the harmonization of TSEP protocols with respect to the neural processes of interest. Further studies should also encounter the potential application of other neuroimaging techniques, such as functional magnetic resonance imaging or positron emission tomography, preferably in combination with TSEP recordings.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009435 Synaptic Transmission The communication from a NEURON to a target (neuron, muscle, or secretory cell) across a SYNAPSE. In chemical synaptic transmission, the presynaptic neuron releases a NEUROTRANSMITTER that diffuses across the synaptic cleft and binds to specific synaptic receptors, activating them. The activated receptors modulate specific ion channels and/or second-messenger systems in the postsynaptic cell. In electrical synaptic transmission, electrical signals are communicated as an ionic current flow across ELECTRICAL SYNAPSES. Neural Transmission,Neurotransmission,Transmission, Neural,Transmission, Synaptic
D009619 Nociceptors Peripheral AFFERENT NEURONS which are sensitive to injuries or pain, usually caused by extreme thermal exposures, mechanical forces, or other noxious stimuli. Their cell bodies reside in the DORSAL ROOT GANGLIA. Their peripheral terminals (NERVE ENDINGS) innervate target tissues and transduce noxious stimuli via axons to the CENTRAL NERVOUS SYSTEM. Pain Receptors,Receptors, Pain,Nociceptive Neurons,Neuron, Nociceptive,Neurons, Nociceptive,Nociceptive Neuron,Nociceptor,Pain Receptor
D011930 Reaction Time The time from the onset of a stimulus until a response is observed. Response Latency,Response Speed,Response Time,Latency, Response,Reaction Times,Response Latencies,Response Times,Speed, Response,Speeds, Response
D012016 Reference Values The range or frequency distribution of a measurement in a population (of organisms, organs or things) that has not been selected for the presence of disease or abnormality. Normal Range,Normal Values,Reference Ranges,Normal Ranges,Normal Value,Range, Normal,Range, Reference,Ranges, Normal,Ranges, Reference,Reference Range,Reference Value,Value, Normal,Value, Reference,Values, Normal,Values, Reference
D005073 Evoked Potentials, Somatosensory The electric response evoked in the CEREBRAL CORTEX by stimulation along AFFERENT PATHWAYS from PERIPHERAL NERVES to CEREBRUM. Somatosensory Evoked Potentials,Evoked Potential, Somatosensory,Somatosensory Evoked Potential
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths

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