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The potential for adverse drug reactions in elderly patients. 2001

L P Gallagher
Pace University, Lienhard School of Nursing, Pleasantville, NY 10709, USA. lgallagher@fsmail.pace.edu

This study examined inappropriately prescribed drugs, inappropriate dosages of drugs, inappropriate combinations of drugs, and numbers of drugs and their potential for causing adverse drug reactions (ADRs) in the elderly. The study also looked at whether the number of diagnoses made a difference in the drugs' potential to cause ADRs. A retrospective audit was made of 146 patients diagnosed with congestive heart failure (CHF) who were admitted to a suburban community agency. Significant correlations were found between the number of medications prescribed and the number of inappropriate medications, the number of medications prescribed and the number of inappropriate dosages of medications, and the number of medications prescribed and the number of potential drug interactions. Multiple diagnoses did not make a difference.

UI MeSH Term Description Entries
D008297 Male Males
D008485 Medical Audit A detailed review and evaluation of selected clinical records by qualified professional personnel for evaluating quality of medical care. Audit, Medical,Audits, Medical,Medical Audits
D009518 New York State bounded on the north by Lake Ontario and Canada, on the east by Vermont, Massachusetts, and Connecticut, on the south by the Atlantic Ocean, New Jersey, and Pennsylvania, and on the west by Pennsylvania, Lake Erie, and Canada.
D002317 Cardiovascular Agents Agents that affect the rate or intensity of cardiac contraction, blood vessel diameter, or blood volume. Cardioactive Agent,Cardioactive Drug,Cardiovascular Agent,Cardiovascular Drug,Cardioactive Agents,Cardioactive Drugs,Cardiovascular Drugs,Agent, Cardioactive,Agent, Cardiovascular,Drug, Cardioactive,Drug, Cardiovascular
D004347 Drug Interactions The action of a drug that may affect the activity, metabolism, or toxicity of another drug. Drug Interaction,Interaction, Drug,Interactions, Drug
D005260 Female Females
D006299 Health Services for the Aged Services for the diagnosis and treatment of diseases in the AGED and the maintenance of health in the ELDERLY. Age-Friendly Health Care,Age-Friendly Health Services,Age-Friendly Health Systems,Geriatric Health Care,Geriatric Health Services,Geriatric Health Systems,Health Care for the Aged,Health Systems for the Aged,Health Services for Aged,Health Services for the Elderly,Health Services, Geriatric,Age Friendly Health Care,Age Friendly Health Services,Age Friendly Health Systems,Age-Friendly Health Cares,Age-Friendly Health Service,Age-Friendly Health System,Care, Age-Friendly Health,Care, Geriatric Health,Cares, Age-Friendly Health,Cares, Geriatric Health,Geriatric Health Cares,Geriatric Health Service,Geriatric Health System,Health Care, Age-Friendly,Health Care, Geriatric,Health Cares, Age-Friendly,Health Cares, Geriatric,Health Service, Age-Friendly,Health Service, Geriatric,Health Services, Age-Friendly,Health System, Age-Friendly,Health System, Geriatric,Health Systems, Age-Friendly,Health Systems, Geriatric,Service, Age-Friendly Health,Service, Geriatric Health,Services, Age-Friendly Health,Services, Geriatric Health,System, Age-Friendly Health,System, Geriatric Health,Systems, Age-Friendly Health,Systems, Geriatric Health
D006333 Heart Failure A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION. Cardiac Failure,Heart Decompensation,Congestive Heart Failure,Heart Failure, Congestive,Heart Failure, Left-Sided,Heart Failure, Right-Sided,Left-Sided Heart Failure,Myocardial Failure,Right-Sided Heart Failure,Decompensation, Heart,Heart Failure, Left Sided,Heart Failure, Right Sided,Left Sided Heart Failure,Right Sided Heart Failure
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly

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