Biomaterial Database

Effect of uncertainty on emotionality and ethanol self-selection in monkeys with cortical ablations. 1975

E R Orloff, and J H Masserman

Alcohol selection and emotionality were examined in rhesus monkeys with frontal cortical ablations which had been subjected to stress via an "uncertainty" paradigm. Uncertainty produced a higher selection of alcohol as compared to nonstress situations. Controls and dorsolateral subjects when exposed to uncertainty selected more of an alcohol solution than either orbital stressed or control-nonstressed animals. Emotionality changes during alcohol-loading and control conditions were measured by recording the number of aggressive or aversive behaviors. Dorsolateral ablations increased the number of aggressive responses while decreasing the number of retreats in the alcohol-loading condition. In the other groups, alcohol loading did not affect the incidence of aggressive or aversive behaviors although they exhibited more retreats than advances across both conditions. Control-nonstressed subjects yielded the lowest number of total aggressive behaviors and the highest number of total retreats.

UI	MeSH Term	Description	Entries
D008253	Macaca mulatta	A species of the genus MACACA inhabiting India, China, and other parts of Asia. The species is used extensively in biomedical research and adapts very well to living with humans.	Chinese Rhesus Macaques,Macaca mulatta lasiota,Monkey, Rhesus,Rhesus Monkey,Rhesus Macaque,Chinese Rhesus Macaque,Macaca mulatta lasiotas,Macaque, Rhesus,Rhesus Macaque, Chinese,Rhesus Macaques,Rhesus Macaques, Chinese,Rhesus Monkeys
D011678	Punishment	The application of an unpleasant stimulus or penalty for the purpose of eliminating or correcting undesirable behavior.	Punishments
D012054	Reinforcement, Psychology	The strengthening of a conditioned response.	Negative Reinforcement,Positive Reinforcement,Psychological Reinforcement,Reinforcement (Psychology),Negative Reinforcements,Positive Reinforcements,Psychological Reinforcements,Psychology Reinforcement,Psychology Reinforcements,Reinforcement, Negative,Reinforcement, Positive,Reinforcement, Psychological,Reinforcements (Psychology),Reinforcements, Negative,Reinforcements, Positive,Reinforcements, Psychological,Reinforcements, Psychology
D004326	Drinking	The consumption of liquids.	Water Consumption,Water Intake,Drinkings
D004558	Electric Stimulation	Use of electric potential or currents to elicit biological responses.	Stimulation, Electric,Electrical Stimulation,Electric Stimulations,Electrical Stimulations,Stimulation, Electrical,Stimulations, Electric,Stimulations, Electrical
D004644	Emotions	Those affective states which can be experienced and have arousing and motivational properties.	Feelings,Regret,Emotion,Feeling,Regrets
D005502	Food	Substances taken in by the body to provide nourishment.	Foods
D005518	Food Preferences	The selection of one food over another.	Food Selection,Food Preference,Food Selections,Preference, Food,Preferences, Food,Selection, Food,Selections, Food
D005625	Frontal Lobe	The part of the cerebral hemisphere anterior to the central sulcus, and anterior and superior to the lateral sulcus.	Brodmann Area 8,Brodmann's Area 8,Frontal Cortex,Frontal Eye Fields,Lobus Frontalis,Supplementary Eye Field,Area 8, Brodmann,Area 8, Brodmann's,Brodmanns Area 8,Cortex, Frontal,Eye Field, Frontal,Eye Field, Supplementary,Eye Fields, Frontal,Frontal Cortices,Frontal Eye Field,Frontal Lobes,Lobe, Frontal,Supplementary Eye Fields
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man