-transparent.png){kind=logo}
B16 melanoma cells were treated in culture with 5-bromo-2-deoxyuridine. The cell-associated and released proteoglycans and sialoglycopeptides were compared to those of control cultures treated with thymidine. The 5-bromo-2-deoxyuridine-treated cultures showed a marked reduction in the proportion of cell-associated proteoglycans and sialoglycopeptides, an increase in the synthesis of hyaluronic acid, the absence of high-molecular-weight chondroitin sulfate, and the presence of increased amounts of heparan sulfate in the media. In addition, the 5-bromo-2-deoxyuridine-treated cells had a higher DNA content and were larger than controls.
Related Publications
C Sato, and
J W Kreider, and
J Banks, and
S Garlick, and
E A Davidson
October 1982,
The Journal of dermatology,
C Sato, and
J W Kreider, and
J Banks, and
S Garlick, and
E A Davidson
November 1972,
Proceedings of the National Academy of Sciences of the United States of America,
C Sato, and
J W Kreider, and
J Banks, and
S Garlick, and
E A Davidson
June 1974,
The Journal of investigative dermatology,
C Sato, and
J W Kreider, and
J Banks, and
S Garlick, and
E A Davidson
January 1977,
FEBS letters,
C Sato, and
J W Kreider, and
J Banks, and
S Garlick, and
E A Davidson
January 1975,
Proceedings of the National Academy of Sciences of the United States of America,
C Sato, and
J W Kreider, and
J Banks, and
S Garlick, and
E A Davidson
January 1976,
International review of cytology,
C Sato, and
J W Kreider, and
J Banks, and
S Garlick, and
E A Davidson
January 1974,
Journal of the National Cancer Institute,
C Sato, and
J W Kreider, and
J Banks, and
S Garlick, and
E A Davidson
August 1977,
Carbohydrate research,
C Sato, and
J W Kreider, and
J Banks, and
S Garlick, and
E A Davidson
June 1977,
Nature,
C Sato, and
J W Kreider, and
J Banks, and
S Garlick, and
E A Davidson
October 1999,
Annals of the New York Academy of Sciences,
