Biomaterial Database

The role of the flocculus of the monkey in saccadic eye movements. 1979

H Noda, and D A Suzuki

1. Purkinje cell discharges were recorded from the flocculus of monkeys either spontaneously making saccadic eye movements (saccades) or trained to fixate a small visual target presented on a tangent screen. In the trained monkeys, saccades of known magnitude and direction were induced by changing the position of the fixation target. 2. Among 513 Purkinje cells, 343 units (66.9%) paused during saccades in all directions (286 units) or in particular directions (57 units). In most units, there were intimate temporal relationships between the beginnings of pauses and saccades, and between the ends of pasuses and saccades. 3. The pause in activity preceded saccades by an average of 9.6 msec, with a maximum lead time of 30 msec. In a fraction of the units (7.6%), the pause started after the onset of saccades. 4. There were 104 units (20.3%) which showed bursts during saccades in all directions (eighty-two units) or in particular directions (twenty-two units). 5. In sixty-six units (12.8%) a burst was associated with saccades in one direction and a pause in the opposite direction. 6. The burst in the burst and burst-pause units preceded saccades by an average of 3.8 msec. There was no significant difference in the lead times between these two groups of units. 7. There was a linear relationship between the duration of the pause in Purkinje cell activity and that of the accompanying saccade. A linear relationship was also seen between the pause duration and the magnitude of saccade.

UI	MeSH Term	Description	Entries
D008251	Macaca	A genus of the subfamily CERCOPITHECINAE, family CERCOPITHECIDAE, consisting of 16 species inhabiting forests of Africa, Asia, and the islands of Borneo, Philippines, and Celebes.	Ape, Barbary,Ape, Black,Ape, Celebes,Barbary Ape,Black Ape,Celebes Ape,Macaque,Apes, Barbary,Apes, Black,Apes, Celebes,Barbary Apes,Black Apes,Celebes Apes,Macacas,Macaques
D009431	Neural Conduction	The propagation of the NERVE IMPULSE along the nerve away from the site of an excitation stimulus.	Nerve Conduction,Conduction, Nerve,Conduction, Neural,Conductions, Nerve,Conductions, Neural,Nerve Conductions,Neural Conductions
D011689	Purkinje Cells	The output neurons of the cerebellar cortex.	Purkinje Cell,Purkinje Neuron,Purkyne Cell,Cell, Purkinje,Cell, Purkyne,Cells, Purkinje,Cells, Purkyne,Neuron, Purkinje,Neurons, Purkinje,Purkinje Neurons,Purkyne Cells
D002531	Cerebellum	The part of brain that lies behind the BRAIN STEM in the posterior base of skull (CRANIAL FOSSA, POSTERIOR). It is also known as the "little brain" with convolutions similar to those of CEREBRAL CORTEX, inner white matter, and deep cerebellar nuclei. Its function is to coordinate voluntary movements, maintain balance, and learn motor skills.	Cerebella,Corpus Cerebelli,Parencephalon,Cerebellums,Parencephalons
D005133	Eye Movements	Voluntary or reflex-controlled movements of the eye.	Eye Movement,Movement, Eye,Movements, Eye
D000200	Action Potentials	Abrupt changes in the membrane potential that sweep along the CELL MEMBRANE of excitable cells in response to excitation stimuli.	Spike Potentials,Nerve Impulses,Action Potential,Impulse, Nerve,Impulses, Nerve,Nerve Impulse,Potential, Action,Potential, Spike,Potentials, Action,Potentials, Spike,Spike Potential
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D000882	Haplorhini	A suborder of PRIMATES consisting of six families: CEBIDAE (some New World monkeys), ATELIDAE (some New World monkeys), CERCOPITHECIDAE (Old World monkeys), HYLOBATIDAE (gibbons and siamangs), CALLITRICHINAE (marmosets and tamarins), and HOMINIDAE (humans and great apes).	Anthropoidea,Monkeys,Anthropoids,Monkey
D012438	Saccades	An abrupt voluntary shift in ocular fixation from one point to another, as occurs in reading.	Pursuit, Saccadic,Saccadic Eye Movements,Eye Movement, Saccadic,Eye Movements, Saccadic,Movement, Saccadic Eye,Movements, Saccadic Eye,Pursuits, Saccadic,Saccade,Saccadic Eye Movement,Saccadic Pursuit,Saccadic Pursuits
D013997	Time Factors	Elements of limited time intervals, contributing to particular results or situations.	Time Series,Factor, Time,Time Factor