Relative pupil-sparing oculomotor nerve palsy as the presenting sign of posterior fossa meningioma. 2001

J M Winterkorn, and M Bruno
Department of Ophthalmology, New York Presbyterian-Weill Cornell University Medical Center, New York, New York, USA. jmswinte@aol.com

We report a case of relative pupil-sparing oculomotor paresis initially attributed to ischemia because weakness of other cranial nerves was minimal and dismissed as insignificant. Neuroimaging eventually revealed a posterior fossa meningioma. The neurologic symptoms and signs disappeared immediately after resection of the tumor. The third nerve palsy was attributed to deformation of the brainstem. This case reinforces the importance of neuroimaging even in patients who have apparently isolated oculomotor palsy with features not classic for an ischemic etiology.

UI MeSH Term Description Entries
D008279 Magnetic Resonance Imaging Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques. Chemical Shift Imaging,MR Tomography,MRI Scans,MRI, Functional,Magnetic Resonance Image,Magnetic Resonance Imaging, Functional,Magnetization Transfer Contrast Imaging,NMR Imaging,NMR Tomography,Tomography, NMR,Tomography, Proton Spin,fMRI,Functional Magnetic Resonance Imaging,Imaging, Chemical Shift,Proton Spin Tomography,Spin Echo Imaging,Steady-State Free Precession MRI,Tomography, MR,Zeugmatography,Chemical Shift Imagings,Echo Imaging, Spin,Echo Imagings, Spin,Functional MRI,Functional MRIs,Image, Magnetic Resonance,Imaging, Magnetic Resonance,Imaging, NMR,Imaging, Spin Echo,Imagings, Chemical Shift,Imagings, Spin Echo,MRI Scan,MRIs, Functional,Magnetic Resonance Images,Resonance Image, Magnetic,Scan, MRI,Scans, MRI,Shift Imaging, Chemical,Shift Imagings, Chemical,Spin Echo Imagings,Steady State Free Precession MRI
D008579 Meningioma A relatively common neoplasm of the CENTRAL NERVOUS SYSTEM that arises from arachnoidal cells. The majority are well differentiated vascular tumors which grow slowly and have a low potential to be invasive, although malignant subtypes occur. Meningiomas have a predilection to arise from the parasagittal region, cerebral convexity, sphenoidal ridge, olfactory groove, and SPINAL CANAL. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2056-7) Benign Meningioma,Malignant Meningioma,Meningiomas, Multiple,Meningiomatosis,Angioblastic Meningioma,Angiomatous Meningioma,Cerebral Convexity Meningioma,Clear Cell Meningioma,Fibrous Meningioma,Hemangioblastic Meningioma,Hemangiopericytic Meningioma,Intracranial Meningioma,Intraorbital Meningioma,Intraventricular Meningioma,Meningotheliomatous Meningioma,Microcystic Meningioma,Olfactory Groove Meningioma,Papillary Meningioma,Parasagittal Meningioma,Posterior Fossa Meningioma,Psammomatous Meningioma,Secretory Meningioma,Sphenoid Wing Meningioma,Spinal Meningioma,Transitional Meningioma,Xanthomatous Meningioma,Angioblastic Meningiomas,Angiomatous Meningiomas,Benign Meningiomas,Cerebral Convexity Meningiomas,Clear Cell Meningiomas,Convexity Meningioma, Cerebral,Convexity Meningiomas, Cerebral,Fibrous Meningiomas,Groove Meningiomas, Olfactory,Hemangioblastic Meningiomas,Hemangiopericytic Meningiomas,Intracranial Meningiomas,Intraorbital Meningiomas,Intraventricular Meningiomas,Malignant Meningiomas,Meningioma, Angioblastic,Meningioma, Angiomatous,Meningioma, Benign,Meningioma, Cerebral Convexity,Meningioma, Clear Cell,Meningioma, Fibrous,Meningioma, Hemangioblastic,Meningioma, Hemangiopericytic,Meningioma, Intracranial,Meningioma, Intraorbital,Meningioma, Intraventricular,Meningioma, Malignant,Meningioma, Meningotheliomatous,Meningioma, Microcystic,Meningioma, Multiple,Meningioma, Olfactory Groove,Meningioma, Papillary,Meningioma, Parasagittal,Meningioma, Posterior Fossa,Meningioma, Psammomatous,Meningioma, Secretory,Meningioma, Sphenoid Wing,Meningioma, Spinal,Meningioma, Transitional,Meningioma, Xanthomatous,Meningiomas,Meningiomas, Angioblastic,Meningiomas, Angiomatous,Meningiomas, Benign,Meningiomas, Cerebral Convexity,Meningiomas, Clear Cell,Meningiomas, Fibrous,Meningiomas, Hemangioblastic,Meningiomas, Hemangiopericytic,Meningiomas, Intracranial,Meningiomas, Intraorbital,Meningiomas, Intraventricular,Meningiomas, Malignant,Meningiomas, Meningotheliomatous,Meningiomas, Microcystic,Meningiomas, Olfactory Groove,Meningiomas, Papillary,Meningiomas, Parasagittal,Meningiomas, Posterior Fossa,Meningiomas, Psammomatous,Meningiomas, Secretory,Meningiomas, Sphenoid Wing,Meningiomas, Spinal,Meningiomas, Transitional,Meningiomas, Xanthomatous,Meningiomatoses,Meningotheliomatous Meningiomas,Microcystic Meningiomas,Multiple Meningioma,Multiple Meningiomas,Olfactory Groove Meningiomas,Papillary Meningiomas,Parasagittal Meningiomas,Posterior Fossa Meningiomas,Psammomatous Meningiomas,Secretory Meningiomas,Sphenoid Wing Meningiomas,Spinal Meningiomas,Transitional Meningiomas,Wing Meningioma, Sphenoid,Wing Meningiomas, Sphenoid,Xanthomatous Meningiomas
D011680 Pupil The aperture in the iris through which light passes. Pupils
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D014792 Visual Acuity Clarity or sharpness of OCULAR VISION or the ability of the eye to see fine details. Visual acuity depends on the functions of RETINA, neuronal transmission, and the interpretative ability of the brain. Normal visual acuity is expressed as 20/20 indicating that one can see at 20 feet what should normally be seen at that distance. Visual acuity can also be influenced by brightness, color, and contrast. Acuities, Visual,Acuity, Visual,Visual Acuities
D015192 Infratentorial Neoplasms Intracranial tumors originating in the region of the brain inferior to the TENTORIUM CEREBELLI, which contains the cerebellum, FOURTH VENTRICLE; CEREBELLOPONTINE ANGLE; BRAIN STEM, and related structures. Primary tumors of this region are more frequent in children, and may present with ATAXIA; CRANIAL NERVE DISEASES; vomiting; HEADACHE; HYDROCEPHALUS; or other signs of neurologic dysfunction. Relatively frequent histologic subtypes include TERATOMA; MEDULLOBLASTOMA; GLIOBLASTOMA; ASTROCYTOMA; EPENDYMOMA; CRANIOPHARYNGIOMA; and choroid plexus papilloma (PAPILLOMA, CHOROID PLEXUS). Infratentorial Tumors,Posterior Fossa Neoplasms,Benign Infratentorial Neoplasms,Infratentorial Cancer,Infratentorial Neoplasms, Benign,Infratentorial Neoplasms, Malignant,Malignant Infratentorial Neoplasms,Neoplasms, Infratentorial,Neoplasms, Posterior Fossa,Posterior Fossa Tumors,Benign Infratentorial Neoplasm,Cancer, Infratentorial,Infratentorial Cancers,Infratentorial Neoplasm,Infratentorial Neoplasm, Benign,Infratentorial Neoplasm, Malignant,Infratentorial Tumor,Malignant Infratentorial Neoplasm,Neoplasm, Benign Infratentorial,Neoplasm, Infratentorial,Neoplasm, Malignant Infratentorial,Neoplasm, Posterior Fossa,Neoplasms, Malignant Infratentorial,Posterior Fossa Neoplasm,Posterior Fossa Tumor,Tumor, Infratentorial,Tumor, Posterior Fossa
D015840 Oculomotor Nerve Diseases Diseases of the oculomotor nerve or nucleus that result in weakness or paralysis of the superior rectus, inferior rectus, medial rectus, inferior oblique, or levator palpebrae muscles, or impaired parasympathetic innervation to the pupil. With a complete oculomotor palsy, the eyelid will be paralyzed, the eye will be in an abducted and inferior position, and the pupil will be markedly dilated. Commonly associated conditions include neoplasms, CRANIOCEREBRAL TRAUMA, ischemia (especially in association with DIABETES MELLITUS), and aneurysmal compression. (From Adams et al., Principles of Neurology, 6th ed, p270) Cranial Nerve III Diseases,Third-Nerve Palsy,Oculomotor Nerve Disorders,Oculomotor Nerve Palsy,Oculomotor Nerve Paralysis,Oculomotor Neuropathy,Partial Third-Nerve Palsy,Third Cranial Nerve Diseases,Third-Nerve Paralysis,Total Third-Nerve Palsy,Nerve Disease, Oculomotor,Nerve Disorder, Oculomotor,Nerve Palsy, Oculomotor,Nerve Paralysis, Oculomotor,Neuropathy, Oculomotor,Oculomotor Nerve Disease,Oculomotor Nerve Disorder,Oculomotor Nerve Palsies,Oculomotor Nerve Paralyses,Oculomotor Neuropathies,Palsy, Oculomotor Nerve,Palsy, Partial Third-Nerve,Palsy, Third-Nerve,Palsy, Total Third-Nerve,Paralysis, Oculomotor Nerve,Paralysis, Third-Nerve,Partial Third Nerve Palsy,Partial Third-Nerve Palsies,Third Nerve Palsy,Third Nerve Paralysis,Third-Nerve Palsies,Third-Nerve Palsies, Partial,Third-Nerve Palsy, Partial,Third-Nerve Palsy, Total,Third-Nerve Paralyses,Total Third Nerve Palsy,Total Third-Nerve Palsies

Related Publications

J M Winterkorn, and M Bruno
July 1990, Archives of neurology,
J M Winterkorn, and M Bruno
December 1983, Annals of neurology,
J M Winterkorn, and M Bruno
April 2024, Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society,
J M Winterkorn, and M Bruno
January 1991, Archives of neurology,
J M Winterkorn, and M Bruno
June 1991, Journal of clinical neuro-ophthalmology,
J M Winterkorn, and M Bruno
May 1999, European journal of neurology,
J M Winterkorn, and M Bruno
January 2023, Journal of neurology,
Copied contents to your clipboard!