Electron microscopic observations of leukocytes from an infant with Chediak-Higashi syndrome-cytochemistry and phagocytic study-.
1975
M Eguchi, and
A Komiyama, and
K Hanamura, and
M Tsukada, and
T Akabane
UI
MeSH Term
Description
Entries
D007223
Infant
A child between 1 and 23 months of age.
Infants
D007962
Leukocytes
White blood cells. These include granular leukocytes (BASOPHILS; EOSINOPHILS; and NEUTROPHILS) as well as non-granular leukocytes (LYMPHOCYTES and MONOCYTES).
The engulfing and degradation of microorganisms; other cells that are dead, dying, or pathogenic; and foreign particles by phagocytic cells (PHAGOCYTES).
Phagocytoses
D002609
Chediak-Higashi Syndrome
A form of phagocyte bactericidal dysfunction characterized by unusual oculocutaneous albinism, high incidence of lymphoreticular neoplasms, and recurrent pyogenic infections. In many cell types, abnormal lysosomes are present leading to defective pigment distribution and abnormal neutrophil functions. The disease is transmitted by autosomal recessive inheritance and a similar disorder occurs in the beige mouse, the Aleutian mink, and albino Hereford cattle.