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31P NMR spectra of the human heart are usually contaminated by signals that originate from blood. The main blood signals are 2,3-diphosphoglycerate (2,3-DPG), which overlap and sometimes obscure the signal of myocardial inorganic phosphate used to calculate intracellular pH and to monitor metabolic changes in the heart. In this work we demonstrate, first, that even without proton decoupling the resolution of such spectra can be high enough to evaluate intracellular inorganic phosphate of myocardium in about 70% of the spectra and, second, that extracellular inorganic phosphate from blood contributes a signal in the chemical shift region of the 2-phosphate signal of 2,3-DPG.
O Schmidt, and
M Bunse, and
G J Dietze, and
O Lutz, and
W I Jung
October 1986,
Biochimica et biophysica acta,
O Schmidt, and
M Bunse, and
G J Dietze, and
O Lutz, and
W I Jung
January 1985,
Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie,
O Schmidt, and
M Bunse, and
G J Dietze, and
O Lutz, and
W I Jung
November 1981,
Proceedings of the National Academy of Sciences of the United States of America,
O Schmidt, and
M Bunse, and
G J Dietze, and
O Lutz, and
W I Jung
July 1988,
Magnetic resonance in medicine,
O Schmidt, and
M Bunse, and
G J Dietze, and
O Lutz, and
W I Jung
August 1996,
NMR in biomedicine,
O Schmidt, and
M Bunse, and
G J Dietze, and
O Lutz, and
W I Jung
September 1993,
FEBS letters,
O Schmidt, and
M Bunse, and
G J Dietze, and
O Lutz, and
W I Jung
July 1988,
The American journal of physiology,
O Schmidt, and
M Bunse, and
G J Dietze, and
O Lutz, and
W I Jung
February 1988,
Proceedings of the National Academy of Sciences of the United States of America,
O Schmidt, and
M Bunse, and
G J Dietze, and
O Lutz, and
W I Jung
November 1984,
Biopolymers,
O Schmidt, and
M Bunse, and
G J Dietze, and
O Lutz, and
W I Jung
January 1992,
NMR in biomedicine,
