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Activity of transketolase, an enzyme of the pentose cycle and fructosodiphosphataldolase, an enzyme of glycolisis was studied in the dynamics of development of the nystatin-producing organism and its inactive mutant under various conditions of their cultivation with a purpose of finding relation between the antibiotic production and general metabolism of Act. noursei. The transketolase activity of the organism was 2-4 times higher than that of the inactive mutant. Addition of 8000 Units/ml of nystatin to the medium markedly suppressed (50-100 per cent) the aldolase activity, however it had no effect on the transkelotase activity. Possibly the antibiotic accumulated in the mycelium played the role of a regulator of the activity of the enzymes, directing the metabolites along the hexosomonophosphate pathway of carbohydrate dissimilation.
E G Toropova, and
R Braĭntling, and
N S Egorov, and
N A Pobedinskiĭ
January 1972,
Mikrobiologiia,
E G Toropova, and
R Braĭntling, and
N S Egorov, and
N A Pobedinskiĭ
January 1963,
Mikrobiologiia,
E G Toropova, and
R Braĭntling, and
N S Egorov, and
N A Pobedinskiĭ
May 1972,
Antibiotiki,
E G Toropova, and
R Braĭntling, and
N S Egorov, and
N A Pobedinskiĭ
June 1973,
Antibiotiki,
E G Toropova, and
R Braĭntling, and
N S Egorov, and
N A Pobedinskiĭ
January 1957,
Antibiotiki,
E G Toropova, and
R Braĭntling, and
N S Egorov, and
N A Pobedinskiĭ
March 1974,
Antibiotiki,
E G Toropova, and
R Braĭntling, and
N S Egorov, and
N A Pobedinskiĭ
August 1999,
FEMS microbiology letters,
E G Toropova, and
R Braĭntling, and
N S Egorov, and
N A Pobedinskiĭ
March 2000,
Microbiology (Reading, England),
E G Toropova, and
R Braĭntling, and
N S Egorov, and
N A Pobedinskiĭ
January 1974,
Patologicheskaia fiziologiia i eksperimental'naia terapiia,
E G Toropova, and
R Braĭntling, and
N S Egorov, and
N A Pobedinskiĭ
June 2005,
Applied microbiology and biotechnology,
