BIOMAT Database Logo BIOMAT Database Logo

[Effects of autogenous periodontal ligament cell transplantation on periodontal tissue regeneration in dogs]. 2000

L Ou, and H Liu, and J Pang
Department of Stomatology, General Hospital of PLA, Beijing 100853, China.

OBJECTIVE To evaluate the effect of autogenous periodontal ligament cell (PDL) transplantation in periodontal tissue regeneration. METHODS PDL cells derived from the same dog were cultured with alpha-MEM. 1 x 10(5) cells of first passage were allowed to attach to the collagen membrane for 24 hours. The membrane-cells were transplanted into periodontal defect in the same dog. Then the defects were covered with e-PTFE membranes. The defects covered only with e-PTFE were the controls. Eighteen teeth of 6 dogs for each group were included. The dogs were sacrificed after 6 weeks. RESULTS The results showed that new bone formation (4.00 +/- 0.13) mm in test group was significantly higher than that of in control group (3.09 +/- 0.28) mm, P < 0.05. The new cementum formation in test group was better than control group (P < 0.05). CONCLUSIONS The results suggested that PDL cell transplantation with guided tissue regeneration technique could enhance periodontal tissue regeneration in dogs.

UI MeSH Term Description Entries
D008297 Male Males
D008567 Membranes, Artificial Artificially produced membranes, such as semipermeable membranes used in artificial kidney dialysis (RENAL DIALYSIS), monomolecular and bimolecular membranes used as models to simulate biological CELL MEMBRANES. These membranes are also used in the process of GUIDED TISSUE REGENERATION. Artificial Membranes,Artificial Membrane,Membrane, Artificial
D010513 Periodontal Ligament The fibrous CONNECTIVE TISSUE surrounding the TOOTH ROOT, separating it from and attaching it to the alveolar bone (ALVEOLAR PROCESS). Alveolodental Ligament,Alveolodental Membrane,Gomphosis,Alveolodental Ligaments,Alveolodental Membranes,Gomphoses,Ligament, Alveolodental,Ligament, Periodontal,Membrane, Alveolodental,Periodontal Ligaments
D002478 Cells, Cultured Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others. Cultured Cells,Cell, Cultured,Cultured Cell
D004285 Dogs The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065) Canis familiaris,Dog
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D014182 Transplantation, Autologous Transplantation of an individual's own tissue from one site to another site. Autografting,Autologous Transplantation,Autotransplantation,Autograftings,Autologous Transplantations,Autotransplantations,Transplantations, Autologous
D016557 Guided Tissue Regeneration, Periodontal Techniques for enhancing and directing cell growth to repopulate specific parts of the PERIODONTIUM that have been damaged by PERIODONTAL DISEASES; TOOTH DISEASES; or TRAUMA, or to correct TOOTH ABNORMALITIES. Repopulation and repair is achieved by guiding the progenitor cells to reproduce in the desired location by blocking contact with surrounding tissue by use of membranes composed of synthetic or natural material that may include growth inducing factors as well. Guided Periodontal Tissue Regeneration,Periodontal Guided Tissue Regeneration,Regeneration, Periodontal Guided Tissue
D017690 Cell Transplantation Transference of cells within an individual, between individuals of the same species, or between individuals of different species. Transplantation, Cell

Related Publications

L Ou, and H Liu, and J Pang
Periodontal regeneration following transplantation of proliferating tissue derived from periodontal ligament into class III furcation defects in dogs.
June 2006, Biomedical research (Tokyo, Japan),
L Ou, and H Liu, and J Pang
Harmine promotes periodontal ligament cell-induced tissue regeneration.
April 2018, Oral diseases,
L Ou, and H Liu, and J Pang
Enhancement of periodontal tissue regeneration by transplantation of osteoprotegerin-engineered periodontal ligament stem cells.
March 2015, Stem cell research & therapy,
L Ou, and H Liu, and J Pang
Application of periodontal ligament cell sheet for periodontal regeneration: a pilot study in beagle dogs.
June 2005, Journal of periodontal research,
L Ou, and H Liu, and J Pang
[Periodontal regeneration after autogenous grafting of cancellous bone tissue and marrow material in dogs (author's transl)].
January 1974, Estomatologia e cultura,
L Ou, and H Liu, and J Pang
Autogenous tooth transplantation: evaluation of pulp tissue regeneration.
November 2011, Medicina oral, patologia oral y cirugia bucal,
L Ou, and H Liu, and J Pang
Periodontal ligament injection: effects on pulp tissue.
December 1985, Journal of endodontics,
L Ou, and H Liu, and J Pang
Tissue Engineering for Periodontal Ligament Regeneration: Biomechanical Specifications.
March 2021, Journal of biomechanical engineering,
L Ou, and H Liu, and J Pang
Periodontal regeneration using periodontal ligament stem cell-transferred amnion.
February 2014, Tissue engineering. Part A,
L Ou, and H Liu, and J Pang
Platelet-rich plasma and autogenous bone graft combined with guided tissue regeneration in periodontal fenestration defects in dogs.
January 2014, The International journal of periodontics & restorative dentistry,
Copied contents to your clipboard!