-transparent.png){kind=logo}
The mutagenicity of benzo[alpha]pyrene and 2-aminoanthracene for Salmonella typhimurium TA98 in the plate-incorporation test was studied using liver S9 from untreated and aroclor-1254-treated rats. The induction of liver S9 protein, arylhydrocarbon hydroxylase (AHH), and cytochrome P448/450 was followed with time. There was no change in protein concentrations with induction; AHH and cytochrome levels were increased at 1, 3, 5 and 7 days post Aroclor treatment. Benzo[alpha]pyrene mutagenicity was enhanced with Aroclor treatment while 2-aminoanthracene mutagenicity was depressed. The benzo[alpha]pyrene mutagenicity showed a positive correlation with the levels of AHH and cytochrome on the plate; 2-aminoanthracene showed a negative correlation with activity in induced samples.
E Zeiger, and
R S Chhabra, and
B H Margolin
December 1986,
Mutation research,
E Zeiger, and
R S Chhabra, and
B H Margolin
April 1984,
Experientia,
E Zeiger, and
R S Chhabra, and
B H Margolin
August 1985,
Toxicology,
E Zeiger, and
R S Chhabra, and
B H Margolin
July 1981,
Cancer letters,
E Zeiger, and
R S Chhabra, and
B H Margolin
July 1981,
Research communications in chemical pathology and pharmacology,
E Zeiger, and
R S Chhabra, and
B H Margolin
November 2000,
Mutation research,
E Zeiger, and
R S Chhabra, and
B H Margolin
July 1979,
Journal - Association of Official Analytical Chemists,
E Zeiger, and
R S Chhabra, and
B H Margolin
June 1986,
Toxicology and applied pharmacology,
E Zeiger, and
R S Chhabra, and
B H Margolin
January 1983,
Mutation research,
E Zeiger, and
R S Chhabra, and
B H Margolin
August 1987,
The Indian journal of medical research,
