Dynamic left ventricular outflow tract obstruction (DLVOTO) has been observed in a variety of clinical circumstances but not previously reported in the setting of orthotopic lung transplantation. Diagnosis and effective management of this adverse event were facilitated by transesophageal echocardiography (TEE). CONCLUSIONS Dynamic left ventricular outflow tract obstruction is not an uncommon phenomenon, but it is often unrecognized. Its rapid recognition and effective treatment was only possible with transesophageal echocardiography (TEE). This contributes to the support for TEE being routinely available for assessment of hemodynamic instability.