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The function of: (see article), fits the tumors weight growth for all studied generations in both control and treated animals. Morphological studies show the transplantable tumors in A mice to lose their similarity to a spontaneous tumor--low differentiated adenocarcinoma. Meanwhile, the tumors in C3H mice have a high differentiation level which is typical for the original tumor. 1-nitroso-1-methylurea is very effective against the first generation of tumors in both strains of mice. The tumors response to the drug becomes weaker with further passages. 1-nitroso-1-methyl urea is superior to other nitrous derivatives when used in such tumor models as breast adenocarcinoma in C3H mice.
L A Ostrovskaia, and
E M Vermel'
January 1970,
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L A Ostrovskaia, and
E M Vermel'
March 1959,
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L A Ostrovskaia, and
E M Vermel'
January 1982,
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L A Ostrovskaia, and
E M Vermel'
June 1985,
Journal of the National Cancer Institute,
L A Ostrovskaia, and
E M Vermel'
October 1957,
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L A Ostrovskaia, and
E M Vermel'
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L A Ostrovskaia, and
E M Vermel'
August 1951,
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L A Ostrovskaia, and
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L A Ostrovskaia, and
E M Vermel'
January 1975,
Voprosy onkologii,
L A Ostrovskaia, and
E M Vermel'
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