Biomaterial Database

Efficacy studies with three formulations of cambendazole in horses. 1975

A Ardans, and G Walters

Treatment with 3 formulations of cambendazole (paste, pellets, and suspension) was compared with thiabendazole treatment in 181 Quarter Horses (females and intact and altered males) of different ages in 2 experiments. The mean output of strongyle eggs, as measured by eggs per gram of feces (epg), was reduced by at least 95% by the 3 formulations of cambendazole compared with pretreatment epg and epg in simultaneously nonmedicated horses. Eggs of Parascaris equorum were seen in 19 of the younger horses in experiment I. Parascaris eggs were not seen in postmedication fecal samples from 14 horses treated wtih cambendazole. Of the 5 horses treated with thiabendazole, 2 had postmedication Parascaris egg counts.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D009349	Nematode Infections	Infections by nematodes, general or unspecified.	Infections, Nematode,Infection, Nematode,Nematode Infection
D002159	Cambendazole	A nematocide effective against a variety of gastrointestinal parasites in cattle, sheep, and horses.	5-Isopropoxycarbonylamino-2-(4-thiazoyl)benzimidazole,Noviben
D005260	Female		Females
D006734	Horse Diseases	Diseases of domestic and wild horses of the species Equus caballus.	Equine Diseases,Disease, Equine,Disease, Horse,Diseases, Equine,Diseases, Horse,Equine Disease,Horse Disease
D006736	Horses	Large, hoofed mammals of the family EQUIDAE. Horses are active day and night with most of the day spent seeking and consuming food. Feeding peaks occur in the early morning and late afternoon, and there are several daily periods of rest.	Equus caballus,Equus przewalskii,Horse, Domestic,Domestic Horse,Domestic Horses,Horse,Horses, Domestic
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D001562	Benzimidazoles	Compounds with a BENZENE fused to IMIDAZOLES.
D013319	Strongyle Infections, Equine	Infection of horses with parasitic nematodes of the superfamily STRONGYLOIDEA. Characteristics include the development of hemorrhagic nodules on the abdominal peritoneum.	Strongylosis, Equine,Equine Strongyle Infections,Infections, Equine Strongyle,Equine Strongyle Infection,Equine Strongyloses,Equine Strongylosis,Infection, Equine Strongyle,Strongyle Infection, Equine,Strongyloses, Equine
D013535	Suspensions	Colloids with liquid continuous phase and solid dispersed phase; the term is used loosely also for solid-in-gas (AEROSOLS) and other colloidal systems; water-insoluble drugs may be given as suspensions.	Suspension