Comparison of fluoride release protocols for in-vitro testing of 3 orthodontic adhesives. 2002

Arthur W Wheeler, and Timothy F Foley, and Antonios Mamandras
Division of Graduate Orthodontics, Faculty of Medicine and Dentistry, University of Western Ontario, Dental Science Building, London, Ontario, Canada N6A 5C1.

The objective of this study was to compare the fluoride release of 3 orthodontic adhesives using disks and bracketed teeth with different storage protocols. The adhesives used were a resin-modified glass ionomer (RMGI) (Fuji Ortho LC; GC America, Aslip, Ill), a polyacid-modified composite resin (PMCR)(Assure; Reliance Orthodontic Products, Itasca, Ill), and a composite control, Transbond XT (3M Unitek, Monrovia, Calif). Metal brackets were bonded to the buccal and lingual surfaces of 120 extracted human premolars. Five plastic containers holding 4 teeth (8 brackets) were used for each adhesive protocol. The samples were stored in containers holding 4 mL of deionized water at 37 degrees C for 28 and 84 days for the brackets and disks, respectively. The bracketed samples released larger initial amounts of fluoride compared with the disk samples during the first 5 to 6 days for both fluoride-releasing adhesives. The PMCR (Assure) released more fluoride (mg/cm(2)/day) than did the RMGI (Fuji Ortho LC) in all protocols with the exception of daily protocols when values diminished below the RMGI values near the 24th day and between the 56th and the 70th days for the bracketed and disk samples, respectively. Inconsistent values for fluoride release were noted in the bracket and disk samples when compared with daily versus cumulative water changes. Daily water changes revealed higher fluoride release levels (brackets), but this trend was not evident in the disk samples. Daily water changes may yield more clinically relevant data on fluoride release.

UI MeSH Term Description Entries
D008422 Materials Testing The testing of materials and devices, especially those used for PROSTHESES AND IMPLANTS; SUTURES; TISSUE ADHESIVES; etc., for hardness, strength, durability, safety, efficacy, and biocompatibility. Biocompatibility Testing,Biocompatible Materials Testing,Hemocompatibility Testing,Testing, Biocompatible Materials,Testing, Hemocompatible Materials,Hemocompatibility Testings,Hemocompatible Materials Testing,Materials Testing, Biocompatible,Materials Testing, Hemocompatible,Testing, Biocompatibility,Testing, Hemocompatibility,Testing, Materials,Testings, Biocompatibility
D011897 Random Allocation A process involving chance used in therapeutic trials or other research endeavor for allocating experimental subjects, human or animal, between treatment and control groups, or among treatment groups. It may also apply to experiments on inanimate objects. Randomization,Allocation, Random
D001840 Dental Bonding An adhesion procedure for orthodontic attachments, such as plastic DENTAL CROWNS. This process usually includes the application of an adhesive material (DENTAL CEMENTS) and letting it harden in-place by light or chemical curing. Bonding, Dental,Cure of Orthodontic Adhesives,Curing, Dental Cement,Dental Cement Curing,Orthodontic Adhesives Cure
D004356 Drug Storage The process of keeping pharmaceutical products in an appropriate location. Drug Storages,Storage, Drug,Storages, Drug
D005459 Fluorides Inorganic salts of hydrofluoric acid, HF, in which the fluorine atom is in the -1 oxidation state. (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) Sodium and stannous salts are commonly used in dentifrices. Fluoride
D005899 Glass Ionomer Cements A polymer obtained by reacting polyacrylic acid with a special anion-leachable glass (alumino-silicate). The resulting cement is more durable and tougher than others in that the materials comprising the polymer backbone do not leach out. Glass Ionomer Cement,Glass Polyalkenoate Cement,Polyalkenoate Cement,Polyalkenoate Cements,Glass Polyalkenoate Cements,Glass-Ionomer Cement,Cement, Glass Ionomer,Cement, Glass Polyalkenoate,Cement, Glass-Ionomer,Cement, Polyalkenoate,Cements, Glass Ionomer,Cements, Glass Polyalkenoate,Cements, Glass-Ionomer,Cements, Polyalkenoate,Glass-Ionomer Cements,Ionomer Cement, Glass,Polyalkenoate Cement, Glass
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000180 Acrylic Resins Polymers of high molecular weight which are derived from acrylic acid, methacrylic acid or other related compounds and are capable of being molded and then hardened to form useful components. Acrylic Resin,Resin, Acrylic,Resins, Acrylic
D000538 Aluminum Silicates Any of the numerous types of clay which contain varying proportions of Al2O3 and SiO2. They are made synthetically by heating aluminum fluoride at 1000-2000 degrees C with silica and water vapor. (From Hawley's Condensed Chemical Dictionary, 11th ed) Aluminum Silicate,Silicate, Aluminum,Silicates, Aluminum
D000704 Analysis of Variance A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable. ANOVA,Analysis, Variance,Variance Analysis,Analyses, Variance,Variance Analyses

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