BIOMAT Database Logo BIOMAT Database Logo

Vitamin A deficiency and genital viral burden in women infected with HIV-1. 2002

Audrey L French, and Mardge H Cohen, and Stephen J Gange, and Harold Burger, and Wei Gao, and Richard D Semba, and William A Meyer, and Esther Robison, and Kathryn Anastos
Division of Infectious Diseases, Durand 115, Cook County Hospital, 1835 West Harrison Street, Chicago, IL 60612, USA. alfrench@ameritech.net

The relation between vitamin A (retinol) deficiency and perinatal transmission of HIV-1, if it exists, might be mediated through an increased viral load in the mother's genital tract. To ascertain whether or not such an association is present, we measured the serum concentration of retinol with high performance liquid chromatography, and correlated the results with concurrent quantified HIV-1 RNA concentrations in cervicovaginal lavage fluid in 301 women infected with the virus. We noted no association between retinol status and genital HIV-1 load. Our findings lend support to those of studies that reported no association between retinol deficiency and perinatal HIV-1 transmission.

UI MeSH Term Description Entries
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D002851 Chromatography, High Pressure Liquid Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed. Chromatography, High Performance Liquid,Chromatography, High Speed Liquid,Chromatography, Liquid, High Pressure,HPLC,High Performance Liquid Chromatography,High-Performance Liquid Chromatography,UPLC,Ultra Performance Liquid Chromatography,Chromatography, High-Performance Liquid,High-Performance Liquid Chromatographies,Liquid Chromatography, High-Performance
D005260 Female Females
D005831 Genital Diseases, Female Pathological processes involving the female reproductive tract (GENITALIA, FEMALE). Gynecologic Diseases,Female Genital Diseases,Diseases, Female Genital,Diseases, Gynecologic,Female Genital Disease,Genital Disease, Female,Gynecologic Disease
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D012307 Risk Factors An aspect of personal behavior or lifestyle, environmental exposure, inborn or inherited characteristic, which, based on epidemiological evidence, is known to be associated with a health-related condition considered important to prevent. Health Correlates,Risk Factor Scores,Risk Scores,Social Risk Factors,Population at Risk,Populations at Risk,Correlates, Health,Factor, Risk,Factor, Social Risk,Factors, Social Risk,Risk Factor,Risk Factor Score,Risk Factor, Social,Risk Factors, Social,Risk Score,Score, Risk,Score, Risk Factor,Social Risk Factor
D012367 RNA, Viral Ribonucleic acid that makes up the genetic material of viruses. Viral RNA
D014801 Vitamin A Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. Dietary vitamin A is derived from a variety of CAROTENOIDS found in plants. It is enriched in the liver, egg yolks, and the fat component of dairy products. Retinol,11-cis-Retinol,3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraen-1-ol, (all-E)-Isomer,All-Trans-Retinol,Aquasol A,Vitamin A1,All Trans Retinol
D014802 Vitamin A Deficiency A nutritional condition produced by a deficiency of VITAMIN A in the diet, characterized by NIGHT BLINDNESS and other ocular manifestations such as dryness of the conjunctiva and later of the cornea (XEROPHTHALMIA). Vitamin A deficiency is a very common problem worldwide, particularly in developing countries as a consequence of famine or shortages of vitamin A-rich foods. In the United States it is found among the urban poor, the elderly, alcoholics, and patients with malabsorption. (From Cecil Textbook of Medicine, 19th ed, p1179) Deficiency, Vitamin A,Deficiencies, Vitamin A,Vitamin A Deficiencies

Related Publications

Audrey L French, and Mardge H Cohen, and Stephen J Gange, and Harold Burger, and Wei Gao, and Richard D Semba, and William A Meyer, and Esther Robison, and Kathryn Anastos
Plasma HIV-1 RNA viral load and serum vitamin A and E levels in HIV-1 infected pregnant women.
February 2000, The Australian & New Zealand journal of obstetrics & gynaecology,
Audrey L French, and Mardge H Cohen, and Stephen J Gange, and Harold Burger, and Wei Gao, and Richard D Semba, and William A Meyer, and Esther Robison, and Kathryn Anastos
Effects of vitamin A supplementation on viral load in HIV-1-infected pregnant women.
May 1997, Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association,
Audrey L French, and Mardge H Cohen, and Stephen J Gange, and Harold Burger, and Wei Gao, and Richard D Semba, and William A Meyer, and Esther Robison, and Kathryn Anastos
HIV-1 RNA in plasma and genital tract secretions in women infected with HIV-1.
October 1999, Journal of acquired immune deficiency syndromes (1999),
Audrey L French, and Mardge H Cohen, and Stephen J Gange, and Harold Burger, and Wei Gao, and Richard D Semba, and William A Meyer, and Esther Robison, and Kathryn Anastos
HIV-1 shedding in genital tract of infected women.
April 2002, Lancet (London, England),
Audrey L French, and Mardge H Cohen, and Stephen J Gange, and Harold Burger, and Wei Gao, and Richard D Semba, and William A Meyer, and Esther Robison, and Kathryn Anastos
HIV-1 shedding in genital tract of infected women.
April 2002, Lancet (London, England),
Audrey L French, and Mardge H Cohen, and Stephen J Gange, and Harold Burger, and Wei Gao, and Richard D Semba, and William A Meyer, and Esther Robison, and Kathryn Anastos
HIV-1 shedding in genital tract of infected women.
April 2002, Lancet (London, England),
Audrey L French, and Mardge H Cohen, and Stephen J Gange, and Harold Burger, and Wei Gao, and Richard D Semba, and William A Meyer, and Esther Robison, and Kathryn Anastos
Plasma and mucosal HIV viral loads are associated with genital tract inflammation in HIV-infected women.
August 2013, Journal of acquired immune deficiency syndromes (1999),
Audrey L French, and Mardge H Cohen, and Stephen J Gange, and Harold Burger, and Wei Gao, and Richard D Semba, and William A Meyer, and Esther Robison, and Kathryn Anastos
Vitamin A deficiency and the acute phase response among HIV-1-infected and -uninfected women in Kenya.
October 2002, Journal of acquired immune deficiency syndromes (1999),
Audrey L French, and Mardge H Cohen, and Stephen J Gange, and Harold Burger, and Wei Gao, and Richard D Semba, and William A Meyer, and Esther Robison, and Kathryn Anastos
Effect of trichomoniasis therapy on genital HIV viral burden among African women.
August 2012, Sexually transmitted diseases,
Audrey L French, and Mardge H Cohen, and Stephen J Gange, and Harold Burger, and Wei Gao, and Richard D Semba, and William A Meyer, and Esther Robison, and Kathryn Anastos
HIV infected women and genital health.
October 1998, Current opinion in obstetrics & gynecology,
Copied contents to your clipboard!