Biomaterial Database

Papaverine and vasospasm. 2002

Erdal Coşkun

UI	MeSH Term	Description	Entries
D010208	Papaverine	An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.	Cerespan,Papaverine Hydrochloride,Pavabid,Pavatym,Hydrochloride, Papaverine
D002986	Clinical Trials as Topic	Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.	Clinical Trial as Topic
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D014665	Vasodilator Agents	Drugs used to cause dilation of the blood vessels.	Vasoactive Antagonists,Vasodilator,Vasodilator Agent,Vasodilator Drug,Vasorelaxant,Vasodilator Drugs,Vasodilators,Vasorelaxants,Agent, Vasodilator,Agents, Vasodilator,Antagonists, Vasoactive,Drug, Vasodilator,Drugs, Vasodilator
D020301	Vasospasm, Intracranial	Constriction of arteries in the SKULL due to sudden, sharp, and often persistent smooth muscle contraction in blood vessels. Intracranial vasospasm results in reduced vessel lumen caliber, restricted blood flow to the brain, and BRAIN ISCHEMIA that may lead to hypoxic-ischemic brain injury (HYPOXIA-ISCHEMIA, BRAIN).	Angiospasm, Intracranial,Cerebral Vasospasm,Intracranial Vasospasm,Cerebral Angiospasm,Cerebral Artery Spasm,Cerebrovascular Spasm,Intracranial Angiospasm,Intracranial Vascular Spasm,Angiospasm, Cerebral,Angiospasms, Cerebral,Angiospasms, Intracranial,Artery Spasm, Cerebral,Artery Spasms, Cerebral,Cerebral Angiospasms,Cerebral Artery Spasms,Cerebral Vasospasms,Cerebrovascular Spasms,Intracranial Angiospasms,Intracranial Vascular Spasms,Intracranial Vasospasms,Spasm, Cerebral Artery,Spasm, Cerebrovascular,Spasm, Intracranial Vascular,Spasms, Cerebral Artery,Spasms, Cerebrovascular,Spasms, Intracranial Vascular,Vascular Spasm, Intracranial,Vascular Spasms, Intracranial,Vasospasm, Cerebral,Vasospasms, Cerebral,Vasospasms, Intracranial