Biomaterial Database

Habituation and inhibition of the crayfish lateral giant fibre escape response. 1975

J J Wine, and F B Krasne, and L Chen

1. Decrement of the lateral giant fibre escape response was studied in intact, restrained, crayfish and in those with the ventral nerve cord transected at the thoracic-abdominal level. 2. Taps (delivered at rates of 1 per 5 min to the abdomen) depressed responsiveness to about 50% of its inital value in 10 trials, for both intact and operated animals. 3. With additional stimulation, responsiveness dropped to near zero for both groups. Recovery was negligible 2 h later, but nearly complete after an additional 24 h rest. 4. Protection against response decrement in this situation was obtained by directly activating the cord giant fibres 30 msec prior to the tactile stimulus. The directly-elicited giant fibre spikes which follow the tactile stimulus do not influence the course of response decrement. 5. The results establish the decrement as centrally mediated habituation, and minimize the role of receptor alterations or descending neuronal influences in the behavioural change. 6. A comparison is made between the properties of hibituation and the homosynaptic depression of afferent to interneurone synapses that is presumed to be the physiological mechanism of habituation in this situation.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008564	Membrane Potentials	The voltage differences across a membrane. For cellular membranes they are computed by subtracting the voltage measured outside the membrane from the voltage measured inside the membrane. They result from differences of inside versus outside concentration of potassium, sodium, chloride, and other ions across cells' or ORGANELLES membranes. For excitable cells, the resting membrane potentials range between -30 and -100 millivolts. Physical, chemical, or electrical stimuli can make a membrane potential more negative (hyperpolarization), or less negative (depolarization).	Resting Potentials,Transmembrane Potentials,Delta Psi,Resting Membrane Potential,Transmembrane Electrical Potential Difference,Transmembrane Potential Difference,Difference, Transmembrane Potential,Differences, Transmembrane Potential,Membrane Potential,Membrane Potential, Resting,Membrane Potentials, Resting,Potential Difference, Transmembrane,Potential Differences, Transmembrane,Potential, Membrane,Potential, Resting,Potential, Transmembrane,Potentials, Membrane,Potentials, Resting,Potentials, Transmembrane,Resting Membrane Potentials,Resting Potential,Transmembrane Potential,Transmembrane Potential Differences
D009132	Muscles	Contractile tissue that produces movement in animals.	Muscle Tissue,Muscle,Muscle Tissues,Tissue, Muscle,Tissues, Muscle
D009413	Nerve Fibers, Myelinated	A class of nerve fibers as defined by their structure, specifically the nerve sheath arrangement. The AXONS of the myelinated nerve fibers are completely encased in a MYELIN SHEATH. They are fibers of relatively large and varied diameters. Their NEURAL CONDUCTION rates are faster than those of the unmyelinated nerve fibers (NERVE FIBERS, UNMYELINATED). Myelinated nerve fibers are present in somatic and autonomic nerves.	A Fibers,B Fibers,Fiber, Myelinated Nerve,Fibers, Myelinated Nerve,Myelinated Nerve Fiber,Myelinated Nerve Fibers,Nerve Fiber, Myelinated
D003400	Astacoidea	A superfamily of various freshwater CRUSTACEA, in the infraorder Astacidea, comprising the crayfish. Common genera include Astacus and Procambarus. Crayfish resemble lobsters, but are usually much smaller.	Astacus,Crayfish,Procambarus,Astacoideas,Crayfishs
D004558	Electric Stimulation	Use of electric potential or currents to elicit biological responses.	Stimulation, Electric,Electrical Stimulation,Electric Stimulations,Electrical Stimulations,Stimulation, Electrical,Stimulations, Electric,Stimulations, Electrical
D004594	Electrophysiology	The study of the generation and behavior of electrical charges in living organisms particularly the nervous system and the effects of electricity on living organisms.
D004924	Escape Reaction	Innate response elicited by sensory stimuli associated with a threatening situation, or actual confrontation with an enemy.	Flight Reaction,Escape Reactions,Flight Reactions,Reaction, Escape,Reaction, Flight,Reactions, Escape,Reactions, Flight
D005260	Female		Females
D006185	Habituation, Psychophysiologic	The disappearance of responsiveness to a repeated stimulation. It does not include drug habituation.	Habituation (Psychophysiology),Habituation, Psychophysiological,Psychophysiologic Habituation,Psychophysiological Habituation,Habituations (Psychophysiology)