BIOMAT Database Logo BIOMAT Database Logo

Tumor suppression by a lymphokine released into the circulation of mice with delayed hypersensitivity. 1975

S B Salvin, and J S Youngner, and J Nishio, and R Neta

Lymphokines such as migration inhibitory factor and type II interferon were released into the circulation of tuberculin-sensitive mice after iv injection of old tuberculin. Daily administration of such sera into the tumor sites of mice given implants of sarcoma MC-36 markedly suppressed tumor growth.

UI MeSH Term Description Entries
D006968 Hypersensitivity, Delayed An increased reactivity to specific antigens mediated not by antibodies but by sensitized T CELLS. Hypersensitivity, Tuberculin-Type,Hypersensitivity, Type IV,Tuberculin-Type Hypersensitivity,Type IV Hypersensitivity,Delayed Hypersensitivity,Delayed Hypersensitivities,Hypersensitivity, Tuberculin Type,Tuberculin Type Hypersensitivity,Tuberculin-Type Hypersensitivities,Type IV Hypersensitivities
D008222 Lymphokines Soluble protein factors generated by activated lymphocytes that affect other cells, primarily those involved in cellular immunity. Lymphocyte Mediators,Mediators, Lymphocyte
D008809 Mice, Inbred C3H An inbred strain of mouse that is used as a general purpose strain in a wide variety of RESEARCH areas including CANCER; INFECTIOUS DISEASES; sensorineural, and cardiovascular biology research. Mice, C3H,Mouse, C3H,Mouse, Inbred C3H,C3H Mice,C3H Mice, Inbred,C3H Mouse,C3H Mouse, Inbred,Inbred C3H Mice,Inbred C3H Mouse
D009000 Monocytes Large, phagocytic mononuclear leukocytes produced in the vertebrate BONE MARROW and released into the BLOOD; contain a large, oval or somewhat indented nucleus surrounded by voluminous cytoplasm and numerous organelles. Monocyte
D009368 Neoplasm Transplantation Experimental transplantation of neoplasms in laboratory animals for research purposes. Transplantation, Neoplasm,Neoplasm Transplantations,Transplantations, Neoplasm
D005260 Female Females
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D012513 Sarcoma, Experimental Experimentally induced neoplasms of CONNECTIVE TISSUE in animals to provide a model for studying human SARCOMA. EHS Tumor,Sarcoma, Engelbreth-Holm-Swarm,Sarcoma, Jensen,Experimental Sarcoma,Experimental Sarcomas,Sarcomas, Experimental,Engelbreth-Holm-Swarm Sarcoma,Jensen Sarcoma,Sarcoma, Engelbreth Holm Swarm,Tumor, EHS
D051379 Mice The common name for the genus Mus. Mice, House,Mus,Mus musculus,Mice, Laboratory,Mouse,Mouse, House,Mouse, Laboratory,Mouse, Swiss,Mus domesticus,Mus musculus domesticus,Swiss Mice,House Mice,House Mouse,Laboratory Mice,Laboratory Mouse,Mice, Swiss,Swiss Mouse,domesticus, Mus musculus

Related Publications

S B Salvin, and J S Youngner, and J Nishio, and R Neta
Suppression of delayed-type hypersensitivity reactions and lymphokine production by cyclosporin A in the mouse.
June 1983, Clinical and experimental immunology,
S B Salvin, and J S Youngner, and J Nishio, and R Neta
Suppression of delayed type hypersensitivity of mice by lead.
May 1977, Experientia,
S B Salvin, and J S Youngner, and J Nishio, and R Neta
[Delayed-type hypersensitivity and lymphokine].
January 1987, Arerugi = [Allergy],
S B Salvin, and J S Youngner, and J Nishio, and R Neta
The differential suppression of antigen, lymphokine and mitogen-induced delayed hypersensitivity-type skin reactions by carrageenan.
January 1973, International archives of allergy and applied immunology,
S B Salvin, and J S Youngner, and J Nishio, and R Neta
Kinetics of the anti-tumor delayed hypersensitivity response in mice with progressively growing tumors: stimulation followed by specific suppression.
February 1974, International journal of cancer,
S B Salvin, and J S Youngner, and J Nishio, and R Neta
[B-cell suppression of delayed hypersensitivity reactions in mice].
February 1986, Arerugi = [Allergy],
S B Salvin, and J S Youngner, and J Nishio, and R Neta
Suppression of delayed-type hypersensitivity in mice by 12-tetradecanoylphorbol-13-acetate.
June 1986, Chemical & pharmaceutical bulletin,
S B Salvin, and J S Youngner, and J Nishio, and R Neta
Suppression of delayed type hypersensitivity by desferoxamine.
April 1991, Journal of immunotherapy : official journal of the Society for Biological Therapy,
S B Salvin, and J S Youngner, and J Nishio, and R Neta
Systemic transfer of tumor immunity: delayed hypersensitivity and suppression of tumor growth.
April 1970, Journal of the National Cancer Institute,
S B Salvin, and J S Youngner, and J Nishio, and R Neta
Viral suppression of delayed hypersensitivity.
January 1972, The Journal of pediatrics,
Copied contents to your clipboard!