Two hundred four patients (117 females, 87 males; age range: 3-80 y) were admitted to our facility between May 1995 and June 1997 and studied to determine the endemicity of the Paederus species, which has been increasing for the last 6 years (especially in May and June) in the Cukurova region of southern Turkey. Clinically, infection with the Paederus species mimics contact dermatitis, herpes zoster, bullous impetigo, and phytophotodermatitis. Definitive diagnosis is made by historical and clinical findings. To determine the main histopathologic features of this infestation, biopsy specimens were obtained from 9 patients and stained with hematoxylin and eosin (H&E). In most patients, the skin lesions were located on the exposed parts of the body. Clinically, these lesions were linear, vesicular, bullous, and/or pustular on erythematous bases and resembled either phytophotodermatitis, herpes zoster, or impetigo rather than classic insect bites. Pederin, which is released from the Paederus species, may cause these lesions. The number of cases has increased markedly during the last 5 years. In the coming years, we expect this number to increase significantly.