[Clomiphene--its use from stimulation test and for treatment of functional sterility]. 1975

G Göretzlehner, and K Rudolf, and R Frahm

There is reported on application of clomiphene (Clostilbegyt-EGYT Pharmaceutical Works, Budapest, Hungaria) in 17 patients for a clomiphene-stimulation-test and in 34 patients with functional sterility on 124 cycles. The dosage was between 50 to 150 mg p.d. for 5 to 7 days and was adapted individually. 12 patients responded to clomiphene-stimulation-test positively and in 4 ovarian hypoplasias and one Anorexia nervosa in acute phase, the clomiphene-stimulation-test was negatively. From the 34 patients with functional sterility 18 women were in 21 times gravid, 13 women could be delivered on term; in 8 cases it was an abortion. By reason of the findings after a clomiphene therapy a gravidity can be accepted, if the hyperthermic phase in the BBT existed for more than 25 days. For a repetition - treatment a dosage is recommended with 150 mg p.d. clomiphene for 7 days.

UI MeSH Term Description Entries
D007247 Infertility, Female Diminished or absent ability of a female to achieve conception. Sterility, Female,Sterility, Postpartum,Sub-Fertility, Female,Subfertility, Female,Female Infertility,Female Sterility,Female Sub-Fertility,Female Subfertility,Postpartum Sterility,Sub Fertility, Female
D010060 Ovulation The discharge of an OVUM from a rupturing follicle in the OVARY. Ovulations
D011085 Polycystic Ovary Syndrome A complex disorder characterized by infertility, HIRSUTISM; OBESITY; and various menstrual disturbances such as OLIGOMENORRHEA; AMENORRHEA; ANOVULATION. Polycystic ovary syndrome is usually associated with bilateral enlarged ovaries studded with atretic follicles, not with cysts. The term, polycystic ovary, is misleading. Stein-Leventhal Syndrome,Polycystic Ovarian Syndrome,Polycystic Ovary Syndrome 1,Sclerocystic Ovarian Degeneration,Sclerocystic Ovaries,Sclerocystic Ovary Syndrome,Ovarian Degeneration, Sclerocystic,Ovarian Syndrome, Polycystic,Ovary Syndrome, Polycystic,Ovary, Sclerocystic,Sclerocystic Ovary,Stein Leventhal Syndrome,Syndrome, Polycystic Ovary,Syndrome, Stein-Leventhal
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D002996 Clomiphene A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue. Note that ENCLOMIPHENE and ZUCLOMIPHENE are the (E) and (Z) isomers of Clomiphene respectively. Chloramiphene,Clomifene,Clomid,Clomide,Clomifen,Clomiphene Citrate,Clomiphene Hydrochloride,Clostilbegit,Dyneric,Gravosan,Klostilbegit,Serophene,Citrate, Clomiphene,Hydrochloride, Clomiphene
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000568 Amenorrhea Absence of menstruation. Postpartum Amenorrhea,Amenorrhea, Postpartum,Postpartum Amenorrheas

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