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Oxibendazole: critical anthelmintic trials in equids. 1975

K C Kates, and M L Colglazier, and F D Enzie

The efficacy of oxibendazole against gastrointestinal parasites of horses was evaluated by the critical test method. Naturally infected ponies of various ages were given single oral doses of 5, 10, or 15 mg-kg of bodyweight. The drug was highly effective against adult large strongylids (Strongylus vulgaris, S edentatus, S equins), adult small strongylids (especially species of the genera Cylicostephanus, Cylicocyclus, Cyaathostomum, and Triodontophorus), and adult and larval stages of the large pinworm, Oxyuris equi. There was no apparent dose-related differences in efficacy. Oxibendazole was less effective against fourth-stage small strongylid larvae than it was against adults. The drug was inactive against stomach bots (Gasterophilus spp), tapeworms (Anoplocephala magna and A perfoliata), lungworms (Dictyocaulus arnfieldi), abdominal worms )Setaria equina), and mature or immature nematodes in locations other than the lumen of the gastrointestinal tract.

UI MeSH Term Description Entries
D009349 Nematode Infections Infections by nematodes, general or unspecified. Infections, Nematode,Infection, Nematode,Nematode Infection
D010123 Oxyuriasis Infection with nematodes of the superfamily OXYUROIDEA. Aspiculariasis,Aspiculariases,Oxyuriases
D010272 Parasitic Diseases Infections or infestations with PARASITES. They are often contracted through contact with an intermediate vector, but may occur as the result of direct exposure. Parasite Infections,Parasitic Infections,Disease, Parasitic,Diseases, Parasitic,Infection, Parasite,Infection, Parasitic,Infections, Parasite,Infections, Parasitic,Parasite Infection,Parasitic Disease,Parasitic Infection
D010273 Parasitic Diseases, Animal Animal diseases caused by PARASITES. Parasitic Infections, Animal,Animal Parasitic Disease,Animal Parasitic Diseases,Animal Parasitic Infection,Animal Parasitic Infections,Disease, Animal Parasitic,Diseases, Animal Parasitic,Infection, Animal Parasitic,Infections, Animal Parasitic,Parasitic Disease, Animal,Parasitic Infection, Animal
D002219 Carbamates Derivatives of carbamic acid, H2NC( Carbamate,Aminoformic Acids,Carbamic Acids,Acids, Aminoformic,Acids, Carbamic
D002590 Cestode Infections Infections with true tapeworms of the helminth subclass CESTODA. Bertielliasis,Cenuriasis,Coenuriasis,Dipylidiasis,Raillietiniasis,Tapeworm Infection,Bertielliases,Cenuriases,Cestode Infection,Coenuriases,Dipylidiases,Infection, Cestode,Infection, Tapeworm,Infections, Cestode,Infections, Tapeworm,Raillietiniases,Tapeworm Infections
D004175 Diptera An order of the class Insecta. Wings, when present, number two and distinguish Diptera from other so-called flies, while the halteres, or reduced hindwings, separate Diptera from other insects with one pair of wings. The order includes the families Calliphoridae, Oestridae, Phoridae, SARCOPHAGIDAE, Scatophagidae, Sciaridae, SIMULIIDAE, Tabanidae, Therevidae, Trypetidae, CERATOPOGONIDAE; CHIRONOMIDAE; CULICIDAE; DROSOPHILIDAE; GLOSSINIDAE; MUSCIDAE; TEPHRITIDAE; and PSYCHODIDAE. The larval form of Diptera species are called maggots (see LARVA). Flies, True,Flies,Dipteras,Fly,Fly, True,True Flies,True Fly
D006734 Horse Diseases Diseases of domestic and wild horses of the species Equus caballus. Equine Diseases,Disease, Equine,Disease, Horse,Diseases, Equine,Diseases, Horse,Equine Disease,Horse Disease
D006736 Horses Large, hoofed mammals of the family EQUIDAE. Horses are active day and night with most of the day spent seeking and consuming food. Feeding peaks occur in the early morning and late afternoon, and there are several daily periods of rest. Equus caballus,Equus przewalskii,Horse, Domestic,Domestic Horse,Domestic Horses,Horse,Horses, Domestic
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia

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