[Temperature limits of mitosis in mammalian cell cultures]. 1975

F V Sushkov, and V V Portugalov

Mammalian cells of different origin (11 strains) were cultivated at the temperature of 25--41 degrees to measure the temperature limits of mitosis. Different strains of the cells reacted to the increase or decrease in the cultivation temperature in a dissimilar way. The difference between the upper temperature limit and the optimum one was not over 5 degrees. Cell division did not end with the temperature fall by over 10 degrees. Various cell strains responded to the temperature decrease in a different way. Most cellular population had three cell types. The majority of the cells were capable of dividing at the threshold temperature; some cells could enter mitosis without completing it and stop at the metaphase. The temperature limits of mitosis were not related to the species and tissue origin of the cells.

UI MeSH Term Description Entries
D008938 Mitosis A type of CELL NUCLEUS division by means of which the two daughter nuclei normally receive identical complements of the number of CHROMOSOMES of the somatic cells of the species. M Phase, Mitotic,Mitotic M Phase,M Phases, Mitotic,Mitoses,Mitotic M Phases,Phase, Mitotic M,Phases, Mitotic M
D002460 Cell Line Established cell cultures that have the potential to propagate indefinitely. Cell Lines,Line, Cell,Lines, Cell
D013696 Temperature The property of objects that determines the direction of heat flow when they are placed in direct thermal contact. The temperature is the energy of microscopic motions (vibrational and translational) of the particles of atoms. Temperatures

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