Biomaterial Database

Effect of dietary amino acids on behavior and serum levels of amino acids in stress loaded rats. 2002

Hideaki Kitajima, and Hidemi Shiomoto, and Kazumi Osada, and Hidehiko Yokogoshi

Laboratory of Nutritional Biochemistry, School of Food and Nutritional Sciences, University of Shizuoka, Japan. h.kitajima@po.rd.taisho.co.jp

Interrelationships between behavior and concentrations of serum amino acids in stressed rats with immobilization and water immersion were investigated. Rats were subjected to 7 h of immobilization with water-immersion stress (IWS) in each sequential day, and serum amino acids were then determined. On the first day, serum taurine, threonine, valine, leucine, isoleucine, phenylalanine, lysine, and histidine (increased-type of amino acids) were significantly increased, but alanine (decreased-type) was significantly decreased. On days 3 and 7, the increase was retained, except for threonine, histidine, and lysine. Spontaneous activities (locomotion, rearing behavior, hole-poking) under loading water-immersion stress were significantly decreased, but a supplementation of branched-chain amino acids (BCAA) led to recovery. We suggest that pretreatment with some kind of increased type of amino acid, such as BCAA, might effectively prevent decline in spontaneous activities evoked by water-immersion stress.

UI	MeSH Term	Description	Entries
D007103	Immobilization	The restriction of the MOVEMENT of whole or part of the body by physical means (RESTRAINT, PHYSICAL) or chemically by ANALGESIA, or the use of TRANQUILIZING AGENTS or NEUROMUSCULAR NONDEPOLARIZING AGENTS. It includes experimental protocols used to evaluate the physiologic effects of immobility.	Hypokinesia, Experimental,Experimental Hypokinesia,Experimental Hypokinesias,Hypokinesias, Experimental
D007700	Kinetics	The rate dynamics in chemical or physical systems.
D008297	Male		Males
D009929	Organ Size	The measurement of an organ in volume, mass, or heaviness.	Organ Volume,Organ Weight,Size, Organ,Weight, Organ
D011392	Proline	A non-essential amino acid that is synthesized from GLUTAMIC ACID. It is an essential component of COLLAGEN and is important for proper functioning of joints and tendons.	L-Proline,L Proline
D001835	Body Weight	The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.	Body Weights,Weight, Body,Weights, Body
D004044	Dietary Proteins	Proteins obtained from foods. They are the main source of the ESSENTIAL AMINO ACIDS.	Proteins, Dietary,Dietary Protein,Protein, Dietary
D004435	Eating	The consumption of edible substances.	Dietary Intake,Feed Intake,Food Intake,Macronutrient Intake,Micronutrient Intake,Nutrient Intake,Nutritional Intake,Ingestion,Dietary Intakes,Feed Intakes,Intake, Dietary,Intake, Feed,Intake, Food,Intake, Macronutrient,Intake, Micronutrient,Intake, Nutrient,Intake, Nutritional,Macronutrient Intakes,Micronutrient Intakes,Nutrient Intakes,Nutritional Intakes
D000090463	Iron Deficiencies	Deficient amounts of iron in the body as a result of blood loss, diets deficient in iron, or an iron uptake or storage disorder.	Hypoferritinemia,Iron Deficiency,Latent Iron Deficiency,Sideropenia,Deficiencies, Iron,Deficiencies, Latent Iron,Deficiency, Iron,Deficiency, Latent Iron,Hypoferritinemias,Iron Deficiencies, Latent,Iron Deficiency, Latent,Latent Iron Deficiencies,Sideropenias
D000596	Amino Acids	Organic compounds that generally contain an amino (-NH2) and a carboxyl (-COOH) group. Twenty alpha-amino acids are the subunits which are polymerized to form proteins.	Amino Acid,Acid, Amino,Acids, Amino