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With the intention to improve the up to now unsatisfying effectiveness of tumour treatment by clostridial spores, the influence of Alloxan-induced hyperlglycemia on clostridial therapy in two transplantable tumours of the rat are examined. Contrary to the isolated clostridial application the combined treatment causes a significant improvement of therapeutic effects (tumour-necrosis and -liquefaction, decreased growth-rate-quotient). The examination of antibody titers against clostridial rods shows in animals with Alloxan-diabetes a more early and more powerful increase in comparison with the isolated clostridial application. The importance of these results for therapy and serological diagnosis of malignant tumours is discussed.
R Ludewig, and
K Hambsch, and
H Kretschmer
January 1980,
Pathologica,
R Ludewig, and
K Hambsch, and
H Kretschmer
December 1977,
Revista brasileira de pesquisas medicas e biologicas,
R Ludewig, and
K Hambsch, and
H Kretschmer
March 1980,
Nihon Shishubyo Gakkai kaishi,
R Ludewig, and
K Hambsch, and
H Kretschmer
September 1981,
Zhonghua nei ke za zhi,
R Ludewig, and
K Hambsch, and
H Kretschmer
June 1979,
Revista espanola de fisiologia,
R Ludewig, and
K Hambsch, and
H Kretschmer
September 1959,
Metabolism: clinical and experimental,
R Ludewig, and
K Hambsch, and
H Kretschmer
March 1979,
Nihon Shishubyo Gakkai kaishi,
R Ludewig, and
K Hambsch, and
H Kretschmer
August 1965,
Diabetes,
R Ludewig, and
K Hambsch, and
H Kretschmer
September 1978,
Nihon Hinyokika Gakkai zasshi. The japanese journal of urology,
R Ludewig, and
K Hambsch, and
H Kretschmer
October 1973,
Deutsche medizinische Wochenschrift (1946),
