In 2000, 22,799 cases of salmonellosis were reported to the sanitary epidemiological stations, incidence rate = 59.0 per 100,000 population. Above 65% of patients were hospitalized. The seasonal peak was noted in May and June. Most of cases (70%) were laboratory confirmed by isolation Salmonella strains types. Salmonella Enteriditis was the most frequent type: 91% of cases and 70% of infected healthy persons. Other serotypes--Typhimurium, Infantis, Hadar and Virchow, caused 5% Salmonella cases only. Seven types not registered in the country up to 2000 were identified (S. Bargny, Kimuenza, Kisii, Limete, Nitra, Rissen, Winterthur). The most affected age group were children under five (337.3/100,000). The most serious clinical syndromes and extraintestinal manifestations like septicaemia, arthritis, meningitis, osteomyelitis pneumonia and other, were observed in 87 patients with at least one non-fecal specimen culture-positive for non-typhoidal Salmonella. In older patients, other diseases like carcinoma, leukaemia, lupus erythematosus, contributed to Salmonella infection. Twelve of those patients had died.