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Bacteremic and leukopenic pneumococcal pneumonia: successful treatment with antibiotics, pulse steroid, and continuous hemodiafiltration. 2002
Toshinobu Yokoyama, and
Teruo Sakamoto, and
Norihiko Shida, and
Toshifumi Shimada, and
Nobuo Kaku, and
Hisamichi Aizawa, and
Kotaro Oizumi
First Department of Internal Medicine, Kurume University School of Medicine, Fukuoka, Japan. yokoyama-t@nyc.odn.ne.jp
We describe a case of bacteremic, leukopenic pneumococcal pneumonia with respiratory failure, accompanied by diabetic ketoacidosis and hypothermia. Pulmonary leukostasis may play a role in the pathogenesis of the acute respiratory distress syndrome (ARDS) in pneumococcal pneumonia. The patient recovered with mechanical ventilation, intravenous antibiotics, pulse-steroid therapy, and continuous hemodiafiltration (CHDF). In particular, administration of steroid and the use of CHDF may improve the status of pulmonary leukostasis in leukopenic pneumococcal infection.
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