Biomaterial Database

Cartilage destruction in rheumatoid arthritis. 2002

S Gay, and S Kuchen, and R E Gay, and M Neidhart

WHO Collaborating Center for Molecular Biology and Novel Therapeutic Strategies for Rheumatic Diseases, Department of Rheumatology, University Hospital, Gloriastrasse 25, CH-8091 Zurich, Switzerland. Steffen.Gay@ruz.usz.ch

UI	MeSH Term	Description	Entries
D002358	Cartilage, Articular	A protective layer of firm, flexible cartilage over the articulating ends of bones. It provides a smooth surface for joint movement, protecting the ends of long bones from wear at points of contact.	Articular Cartilage,Articular Cartilages,Cartilages, Articular
D005347	Fibroblasts	Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.	Fibroblast
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001172	Arthritis, Rheumatoid	A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.	Rheumatoid Arthritis
D013583	Synovial Membrane	The inner membrane of a joint capsule surrounding a freely movable joint. It is loosely attached to the external fibrous capsule and secretes SYNOVIAL FLUID.	Synovium,Membrana Synovialis Capsulae Articularis,Membrane, Synovial,Membranes, Synovial,Synovial Membranes
D020084	Long Interspersed Nucleotide Elements	Highly repeated sequences, 6K-8K base pairs in length, which contain RNA polymerase II promoters. They also have an open reading frame that is related to the reverse transcriptase of retroviruses but they do not contain LTRs (long terminal repeats). Copies of the LINE 1 (L1) family form about 15% of the human genome. The jockey elements of Drosophila are LINEs.	Jockey Elements,L1 Elements,LINE-1 Elements,Long Interspersed DNA Sequence Elements,LINE Repeat Sequences,Element, Jockey,Element, L1,Element, LINE-1,Elements, Jockey,Elements, L1,Elements, LINE-1,Jockey Element,L1 Element,LINE 1 Elements,LINE Repeat Sequence,LINE-1 Element,Repeat Sequence, LINE,Repeat Sequences, LINE,Sequence, LINE Repeat,Sequences, LINE Repeat