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The primary objective was to develop a telemetric oxygen sensor designed for implantation in subcutaneous tissue. In the sensor, the platinum indicating electrode was covered with polythene to retard oxygen entry and avoid interference. Given the potential for large indicating electrodes to deplete oxygen in vivo, some sensors were made with very small indicating electrodes. Sensors were tested in the anesthetized rabbit at various oxygen concentrations. Animals were studied 1 and 5 days after implementation. The sensor could detect changes in oxygen in vivo. Measurements were similar at 1 and 5 days and sensors with different sized electrodes yielded similar results. This telemetric implantable amperometric sensor can detect variations in tissue oxygenation and may have applications in cardiopulmonary physiology, continuous glucose monitoring and other related fields.
W K Ward, and
M D Wood, and
E P Slobodzian
July 2006,
Analytica chimica acta,
W K Ward, and
M D Wood, and
E P Slobodzian
June 2013,
American journal of physiology. Renal physiology,
W K Ward, and
M D Wood, and
E P Slobodzian
November 2008,
IEEE transactions on bio-medical engineering,
W K Ward, and
M D Wood, and
E P Slobodzian
May 1998,
Proceedings of the National Academy of Sciences of the United States of America,
W K Ward, and
M D Wood, and
E P Slobodzian
July 2019,
Microvascular research,
W K Ward, and
M D Wood, and
E P Slobodzian
September 1997,
Talanta,
W K Ward, and
M D Wood, and
E P Slobodzian
July 2018,
JAMA internal medicine,
W K Ward, and
M D Wood, and
E P Slobodzian
January 1986,
Acta biochimica et biophysica Hungarica,
W K Ward, and
M D Wood, and
E P Slobodzian
September 2011,
BMC research notes,
W K Ward, and
M D Wood, and
E P Slobodzian
January 1982,
Journal of perinatal medicine,
