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A double labeling method with two levels of tritiated thymidine was used to study 6 patients with seborrheic keratosis, 1 with a fibroepithelial tumor of Pinkus, and 1 with basal cell nevus syndrome manifesting three pits on the palm of the hand. The two latter types of lesions, known to be able to evolve into basal cell carcinoma, had an increased S-phase duration (18 hr for the germ cells of the palmar pits) as compared with normal epidermis (10 hr). This situation was similar to that observed in basal cell carcinoma, However, the S phase was not lengthened in seborrheic keratosis (9.2 plus or minus 1.6), a benign tumor in which malignant transformation is extremely rare. S phase was also of normal duration in the benign eosinophilic septa of the tumor of Pinkus.
M Heenen, and
J C Lambert, and
G Achten, and
P Galand
September 1968,
Cancer,
M Heenen, and
J C Lambert, and
G Achten, and
P Galand
January 1977,
International journal of dermatology,
M Heenen, and
J C Lambert, and
G Achten, and
P Galand
June 1955,
Comptes rendus hebdomadaires des seances de l'Academie des sciences,
M Heenen, and
J C Lambert, and
G Achten, and
P Galand
January 1974,
Acta dermato-venereologica,
M Heenen, and
J C Lambert, and
G Achten, and
P Galand
October 1971,
The Journal of investigative dermatology,
M Heenen, and
J C Lambert, and
G Achten, and
P Galand
January 1978,
Meditsinskaia radiologiia,
M Heenen, and
J C Lambert, and
G Achten, and
P Galand
June 1978,
The Journal of investigative dermatology,
M Heenen, and
J C Lambert, and
G Achten, and
P Galand
March 1975,
The Laryngoscope,
M Heenen, and
J C Lambert, and
G Achten, and
P Galand
December 1976,
Cancer treatment reports,
M Heenen, and
J C Lambert, and
G Achten, and
P Galand
June 1973,
Pathologie-biologie,
