Peritoneal fluid, endometriosis, and ciliary beat frequency in the human fallopian tube. 2002

Rachel A Lyons, and Ovrang Djahanbakhch, and Ertan Saridogan, and Alan A Naftalin, and Tariq Mahmood, and Anthony Weekes, and Rashna Chenoy
Academic Department of Obstetrics and Gynaecology, St Bartholomew's Hospital and The London School of Medicine and Dentistry, London, UK.

Endometriosis and infertility are known to be associated, but it is unclear whether endometriosis causes infertility. We used contrast analogue enhancement to study the effect of peritoneal fluid from women with early stage endometriosis on the ciliary beat frequency of human fallopian tube epithelium. We obtained peritoneal fluid from six women with early stage endometriosis and from six fertile women with no evidence of endometriosis to use as controls. Fallopian tubes from hysterectomy specimens were collected from 17 women. The difference in ciliary beat frequency between fallopian tubes exposed to peritoneal fluids of women with and without endometriosis increased with the duration of incubation (mean difference at 24 h 1.35 Hz, 95% CI 0.94-1.75, p=0.01). At 24 h, ciliary beat frequency was significantly lower in the incubations with peritoneal fluid from women with endometriosis than controls (4.29 [0.15] vs 5.64 Hz [0.15], respectively, p=0.001). Impairment of ciliary action in women with endometriosis might reduce fertility.

UI MeSH Term Description Entries
D007247 Infertility, Female Diminished or absent ability of a female to achieve conception. Sterility, Female,Sterility, Postpartum,Sub-Fertility, Female,Subfertility, Female,Female Infertility,Female Sterility,Female Sub-Fertility,Female Subfertility,Postpartum Sterility,Sub Fertility, Female
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D002923 Cilia Populations of thin, motile processes found covering the surface of ciliates (CILIOPHORA) or the free surface of the cells making up ciliated EPITHELIUM. Each cilium arises from a basic granule in the superficial layer of CYTOPLASM. The movement of cilia propels ciliates through the liquid in which they live. The movement of cilia on a ciliated epithelium serves to propel a surface layer of mucus or fluid. (King & Stansfield, A Dictionary of Genetics, 4th ed) Motile Cilia,Motile Cilium,Nodal Cilia,Nodal Cilium,Primary Cilia,Primary Cilium,Cilium,Cilia, Motile,Cilia, Nodal,Cilia, Primary,Cilium, Motile,Cilium, Nodal,Cilium, Primary
D004715 Endometriosis A condition in which functional endometrial tissue is present outside the UTERUS. It is often confined to the PELVIS involving the OVARY, the ligaments, cul-de-sac, and the uterovesical peritoneum. Endometrioma,Endometriomas,Endometrioses
D005187 Fallopian Tubes A pair of highly specialized canals extending from the UTERUS to its corresponding OVARY. They provide the means for OVUM transport from the ovaries and they are the site of the ovum's final maturation and FERTILIZATION. The fallopian tube consists of an interstitium, an isthmus, an ampulla, an infundibulum, and fimbriae. Its wall consists of three layers: serous, muscular, and an internal mucosal layer lined with both ciliated and secretory cells. Oviducts, Mammalian,Salpinges, Uterine,Salpinx, Uterine,Uterine Salpinges,Uterine Salpinx,Fallopian Tube,Uterine Tubes,Mammalian Oviduct,Mammalian Oviducts,Oviduct, Mammalian,Tube, Fallopian,Tube, Uterine,Tubes, Fallopian,Tubes, Uterine,Uterine Tube
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000704 Analysis of Variance A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable. ANOVA,Analysis, Variance,Variance Analysis,Analyses, Variance,Variance Analyses
D001202 Ascitic Fluid The serous fluid of ASCITES, the accumulation of fluids in the PERITONEAL CAVITY. Peritoneal Effusion,Peritoneal Fluid,Ascitic Fluids,Effusion, Peritoneal,Fluid, Ascitic,Fluid, Peritoneal,Peritoneal Effusions,Peritoneal Fluids

Related Publications

Rachel A Lyons, and Ovrang Djahanbakhch, and Ertan Saridogan, and Alan A Naftalin, and Tariq Mahmood, and Anthony Weekes, and Rashna Chenoy
May 2018, Reproductive biology and endocrinology : RB&E,
Rachel A Lyons, and Ovrang Djahanbakhch, and Ertan Saridogan, and Alan A Naftalin, and Tariq Mahmood, and Anthony Weekes, and Rashna Chenoy
November 1998, Human reproduction (Oxford, England),
Rachel A Lyons, and Ovrang Djahanbakhch, and Ertan Saridogan, and Alan A Naftalin, and Tariq Mahmood, and Anthony Weekes, and Rashna Chenoy
May 2010, Reproductive biology and endocrinology : RB&E,
Rachel A Lyons, and Ovrang Djahanbakhch, and Ertan Saridogan, and Alan A Naftalin, and Tariq Mahmood, and Anthony Weekes, and Rashna Chenoy
July 2010, Experimental physiology,
Rachel A Lyons, and Ovrang Djahanbakhch, and Ertan Saridogan, and Alan A Naftalin, and Tariq Mahmood, and Anthony Weekes, and Rashna Chenoy
May 2013, Reproductive biology and endocrinology : RB&E,
Rachel A Lyons, and Ovrang Djahanbakhch, and Ertan Saridogan, and Alan A Naftalin, and Tariq Mahmood, and Anthony Weekes, and Rashna Chenoy
March 1951, Geburtshilfe und Frauenheilkunde,
Rachel A Lyons, and Ovrang Djahanbakhch, and Ertan Saridogan, and Alan A Naftalin, and Tariq Mahmood, and Anthony Weekes, and Rashna Chenoy
October 2011, Biomedical research (Tokyo, Japan),
Rachel A Lyons, and Ovrang Djahanbakhch, and Ertan Saridogan, and Alan A Naftalin, and Tariq Mahmood, and Anthony Weekes, and Rashna Chenoy
January 1981, The American review of respiratory disease,
Rachel A Lyons, and Ovrang Djahanbakhch, and Ertan Saridogan, and Alan A Naftalin, and Tariq Mahmood, and Anthony Weekes, and Rashna Chenoy
March 1997, Chest,
Rachel A Lyons, and Ovrang Djahanbakhch, and Ertan Saridogan, and Alan A Naftalin, and Tariq Mahmood, and Anthony Weekes, and Rashna Chenoy
November 2001, The Annals of otology, rhinology, and laryngology,
Copied contents to your clipboard!