Biomaterial Database

Effect of temperature on synaptic transmission between identified neurones of the mollusc Lymnaea stagnalis. 2002

Alexander V Sidorov

Department of Physiology, Belarusian State University, Minsk, 220050, Belarus. sidorov@bsu.by

The mollusc, Lymnaea stagnalis, has been used as a model to study the mechanisms of temperature-dependent processes in the central nervous system. Effects of temperature changes on transmission in monosynaptic connections, made by the FMRFamide-containing neurone VD4 and the giant dopaminergic neurone RPeD1 with follower neurones, were recorded with intracellular microelectrodes. In the temperature range of 4-6 degrees C, inhibitory postsynaptic potentials (IPSP) in response to VD4 stimulation were not observed in postsynaptic cells while the IPSPs persisted in the RPeD1 followers. A temperature rise resulted in a sharp increase in the IPSP amplitude in followers of both VD4 and RPeD1. In isolated nervous systems taken from molluscs which have been kept at 4-6 degrees C for 2 weeks and more, no coupling between VD4, RPeD1 and synaptically connected cells was seen in the full experimental temperature range. The synaptic coupling recovered only after maintaining the molluscs at a water temperature of 14-16 degrees C for at least 2 days. The changes observed in synaptic responses to temperature alterations correspond to the behaviour of the molluscs.

UI	MeSH Term	Description	Entries
D008195	Lymnaea	A genus of dextrally coiled freshwater snails that includes some species of importance as intermediate hosts of parasitic flukes.	Lymnea,Lymnaeas,Lymneas
D009435	Synaptic Transmission	The communication from a NEURON to a target (neuron, muscle, or secretory cell) across a SYNAPSE. In chemical synaptic transmission, the presynaptic neuron releases a NEUROTRANSMITTER that diffuses across the synaptic cleft and binds to specific synaptic receptors, activating them. The activated receptors modulate specific ion channels and/or second-messenger systems in the postsynaptic cell. In electrical synaptic transmission, electrical signals are communicated as an ionic current flow across ELECTRICAL SYNAPSES.	Neural Transmission,Neurotransmission,Transmission, Neural,Transmission, Synaptic
D009474	Neurons	The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.	Nerve Cells,Cell, Nerve,Cells, Nerve,Nerve Cell,Neuron
D003080	Cold Temperature	An absence of warmth or heat or a temperature notably below an accustomed norm.	Cold,Cold Temperatures,Temperature, Cold,Temperatures, Cold
D006358	Hot Temperature	Presence of warmth or heat or a temperature notably higher than an accustomed norm.	Heat,Hot Temperatures,Temperature, Hot,Temperatures, Hot
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D013696	Temperature	The property of objects that determines the direction of heat flow when they are placed in direct thermal contact. The temperature is the energy of microscopic motions (vibrational and translational) of the particles of atoms.	Temperatures