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Intravenous glucagon: does it optimize evaluation of the gastrointestinal tract on helical CT? 2002

Recha S Eisenstat, and Burton M Gold, and Lori Goffner, and Arthur A Fruauff, and Simcha Pollack, and Douglas S Katz
Department of Radiology, Winthrop-University Hospital, 259 First Street Mineola, NY 11501, USA.

Forty outpatients were randomized into two groups of 20. Twenty patients received 1 mg of intravenous glucagon and the other 20 did not. Three radiologists evaluated the bowel using a qualitative score and mean scores for each bowel level were compared. A different radiologist measured the maximal diameter of bowel at seven levels. There were no significant differences in qualitative or quantitative data for the two groups. Intravenous glucagon is therefore not routinely recommended for helical CT of the abdomen.

UI MeSH Term Description Entries
D007275 Injections, Intravenous Injections made into a vein for therapeutic or experimental purposes. Intravenous Injections,Injection, Intravenous,Intravenous Injection
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D003287 Contrast Media Substances used to allow enhanced visualization of tissues. Radiopaque Media,Contrast Agent,Contrast Agents,Contrast Material,Contrast Materials,Radiocontrast Agent,Radiocontrast Agents,Radiocontrast Media,Agent, Contrast,Agent, Radiocontrast,Agents, Contrast,Agents, Radiocontrast,Material, Contrast,Materials, Contrast,Media, Contrast,Media, Radiocontrast,Media, Radiopaque
D004064 Digestive System A group of organs stretching from the MOUTH to the ANUS, serving to breakdown foods, assimilate nutrients, and eliminate waste. In humans, the digestive system includes the GASTROINTESTINAL TRACT and the accessory glands (LIVER; BILIARY TRACT; PANCREAS). Ailmentary System,Alimentary System
D005260 Female Females
D005934 Glucagon A 29-amino acid pancreatic peptide derived from proglucagon which is also the precursor of intestinal GLUCAGON-LIKE PEPTIDES. Glucagon is secreted by PANCREATIC ALPHA CELLS and plays an important role in regulation of BLOOD GLUCOSE concentration, ketone metabolism, and several other biochemical and physiological processes. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1511) Glucagon (1-29),Glukagon,HG-Factor,Hyperglycemic-Glycogenolytic Factor,Proglucagon (33-61),HG Factor,Hyperglycemic Glycogenolytic Factor
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013997 Time Factors Elements of limited time intervals, contributing to particular results or situations. Time Series,Factor, Time,Time Factor
D036542 Tomography, Spiral Computed Computed tomography where there is continuous X-ray exposure to the patient while being transported in a spiral or helical pattern through the beam of irradiation. This provides improved three-dimensional contrast and spatial resolution compared to conventional computed tomography, where data is obtained and computed from individual sequential exposures. CAT Scan, Spiral,CT Scan, Spiral,Helical CT,Helical Computed Tomography,Spiral CT,Spiral Computed Tomography,Tomography, Helical Computed,Computed Tomography, Spiral,Computer-Assisted Tomography, Spiral,Computerized Tomography, Spiral,CAT Scans, Spiral,CT Scans, Spiral,CT, Helical,CT, Spiral,CTs, Helical,CTs, Spiral,Computed Tomography, Helical,Computer Assisted Tomography, Spiral,Helical CTs,Scan, Spiral CAT,Scan, Spiral CT,Scans, Spiral CAT,Scans, Spiral CT,Spiral CAT Scan,Spiral CAT Scans,Spiral CT Scan,Spiral CT Scans,Spiral CTs,Spiral Computer-Assisted Tomography,Spiral Computerized Tomography,Tomography, Spiral Computer-Assisted,Tomography, Spiral Computerized

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