Biomaterial Database

[Effects of 7 d head down tilt on cardiopulmonary circulation during orthostasis]. 1999

D S Wang, and Q L Xiang, and X Y Shen, and J R Meng, and Q Dong

Institute of Space Medico-Engineering, Beijing, China.

Objective. To accumulate data for further studies on the mechanisms of the decrease of cardiovascular function after weightlessness. Method. Cardiopulmonary circulatory function under supine position and head up tilting (HUT) for 20 min before and after exposure to 7 d 6 degrees head down tilt (HDT) in 6 healthy adults who aged 19-21 were measured with a XXH-2000 lesser (pulmonary) circulation and cardiac function instrument. Result. The 7 d HDT resulted in orthostatic intolerance of the subjects; the reduction of RVET (j-z) and the elevation of RPEP [RVET(Q-j)/(j - z)] indicated a decrease of the right heart function. An obvious decrease of the right heart reserves was also observed under HUT after HDT. Conclusion. hc and hc/hz were demonstrated to be useful parameters to evaluate orthostatic tolerance or to forecast orthostatic syncope. The lesser (pulmonary) circulation and cardiac function testing methods are valuable in evaluating the cardiopulmonary circulatory function during HUT.

UI	MeSH Term	Description	Entries
D007024	Hypotension, Orthostatic	A significant drop in BLOOD PRESSURE after assuming a standing position. Orthostatic hypotension is a finding, and defined as a 20-mm Hg decrease in systolic pressure or a 10-mm Hg decrease in diastolic pressure 3 minutes after the person has risen from supine to standing. Symptoms generally include DIZZINESS, blurred vision, and SYNCOPE.	Hypotension, Postural,Orthostatic Hypotension,Postural Hypotension
D011187	Posture	The position or physical attitude of the body.	Postures
D011652	Pulmonary Circulation	The circulation of the BLOOD through the LUNGS.	Pulmonary Blood Flow,Respiratory Circulation,Circulation, Pulmonary,Circulation, Respiratory,Blood Flow, Pulmonary,Flow, Pulmonary Blood,Pulmonary Blood Flows
D003326	Coronary Circulation	The circulation of blood through the CORONARY VESSELS of the HEART.	Circulation, Coronary
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D000337	Aerospace Medicine	That branch of medicine dealing with the studies and effects of flight through the atmosphere or in space upon the human body and with the prevention or cure of physiological or psychological malfunctions arising from these effects. (from NASA Thesaurus)	Aviation Medicine,Space Medicine,Medicine, Aerospace,Medicine, Aviation,Medicine, Space
D001510	Bed Rest	Confinement of an individual to bed for therapeutic or experimental reasons.	Bedrest,Bed Rests,Bedrests,Rest, Bed,Rests, Bed
D013575	Syncope	A transient loss of consciousness and postural tone caused by diminished blood flow to the brain (i.e., BRAIN ISCHEMIA). Presyncope refers to the sensation of lightheadedness and loss of strength that precedes a syncopal event or accompanies an incomplete syncope. (From Adams et al., Principles of Neurology, 6th ed, pp367-9)	Drop Attack,Fainting,Presyncope,Syncope, Postural,Syncopal Episode,Syncopal Vertigo,Syncope, Cardiogenic,Syncope, Carotid Sinus,Syncope, Convulsive,Syncope, Deglutitional,Syncope, Effort,Syncope, Hyperventilation,Syncope, Micturition,Syncope, Situational,Syncope, Stokes-Adams,Syncope, Tussive,Attack, Drop,Cardiogenic Syncope,Cardiogenic Syncopes,Carotid Sinus Syncope,Carotid Sinus Syncopes,Convulsive Syncope,Convulsive Syncopes,Deglutitional Syncope,Deglutitional Syncopes,Drop Attacks,Effort Syncope,Effort Syncopes,Episode, Syncopal,Hyperventilation Syncope,Hyperventilation Syncopes,Micturition Syncope,Micturition Syncopes,Postural Syncope,Postural Syncopes,Presyncopes,Situational Syncope,Situational Syncopes,Stokes-Adams Syncope,Stokes-Adams Syncopes,Syncopal Episodes,Syncope, Stokes Adams,Syncopes,Syncopes, Cardiogenic,Syncopes, Carotid Sinus,Syncopes, Convulsive,Syncopes, Deglutitional,Syncopes, Effort,Syncopes, Hyperventilation,Syncopes, Micturition,Syncopes, Postural,Syncopes, Situational,Syncopes, Stokes-Adams,Syncopes, Tussive,Tussive Syncope,Tussive Syncopes,Vertigo, Syncopal,Vertigos, Syncopal
D016683	Supine Position	The posture of an individual lying face up.	Dorsal Position,Dorsal Positions,Position, Dorsal,Position, Supine,Positions, Dorsal,Positions, Supine,Supine Positions