Biomaterial Database

Serum gastrin level in early childhood. 1975

L Sann, and A P Chayvialle, and A Bremond, and R Lambert

Serum gastrin concentration was measured in newborns and infants with no gastrointestinal disorders, in the fasting state and after food stimulation. Mean fasting concentration in 14 newborns aged 1 to 12 days (130 . 4 pg/ml +/- 11 . 4 SE) was significantly higher than the mean value in 23 infants aged 1.5 to 22 months (101.4 +/- 6.6 pg/ml). Ingestion of the usual milk meal resulted in a definite rise of the serum gastrin level in the 5 subjects tested (3 newborns and 2 infants). The mean fasting serum gastrin level in 6 babies with hiatus hernia and gastro-oesophageal reflux was found to be no different from the corresponding value in 8 age-matched controls. However, a conspicuously raised fasting gastrin concentration was observed in one infant with lower oesophageal dyskinesia. The results indicate that the release of gastrin and the reactivity of the hormone-producing sites to food stimulation in early life are similar to those in adult humans. No defect of gastrin release was shown in patients with gastro-oesophageal reflux.

UI	MeSH Term	Description	Entries
D007223	Infant	A child between 1 and 23 months of age.	Infants
D007231	Infant, Newborn	An infant during the first 28 days after birth.	Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D008892	Milk	The off-white liquid secreted by the mammary glands of humans and other mammals. It contains proteins, sugar, lipids, vitamins, and minerals.	Cow Milk,Cow's Milk,Milk, Cow,Milk, Cow's
D004935	Esophageal Diseases	Pathological processes in the ESOPHAGUS.	Disease, Esophageal,Diseases, Esophageal,Esophageal Disease
D005755	Gastrins	A family of gastrointestinal peptide hormones that excite the secretion of GASTRIC JUICE. They may also occur in the central nervous system where they are presumed to be neurotransmitters.	Gastrin
D005764	Gastroesophageal Reflux	Retrograde flow of gastric juice (GASTRIC ACID) and/or duodenal contents (BILE ACIDS; PANCREATIC JUICE) into the distal ESOPHAGUS, commonly due to incompetence of the LOWER ESOPHAGEAL SPHINCTER.	Esophageal Reflux,Gastro-Esophageal Reflux Disease,GERD,Gastric Acid Reflux,Gastric Acid Reflux Disease,Gastro-Esophageal Reflux,Gastro-oesophageal Reflux,Gastroesophageal Reflux Disease,Reflux, Gastroesophageal,Acid Reflux, Gastric,Gastro Esophageal Reflux,Gastro Esophageal Reflux Disease,Gastro oesophageal Reflux,Gastro-Esophageal Reflux Diseases,Reflux Disease, Gastro-Esophageal,Reflux, Gastric Acid,Reflux, Gastro-Esophageal,Reflux, Gastro-oesophageal
D006551	Hernia, Hiatal	STOMACH herniation located at or near the diaphragmatic opening for the ESOPHAGUS, the esophageal hiatus.	Hernia, Esophageal,Hernia, Paraesophageal,Hiatal Hernia,Esophageal Hernia,Hernia, Hiatus,Paraesophageal Hiatal Hernia,Sliding Esophageal Hernia,Sliding Hiatal Hernia,Esophageal Hernia, Sliding,Esophageal Hernias,Esophageal Hernias, Sliding,Hernia, Paraesophageal Hiatal,Hernia, Sliding Esophageal,Hernia, Sliding Hiatal,Hernias, Esophageal,Hernias, Hiatal,Hernias, Hiatus,Hernias, Paraesophageal,Hernias, Paraesophageal Hiatal,Hernias, Sliding Esophageal,Hernias, Sliding Hiatal,Hiatal Hernia, Paraesophageal,Hiatal Hernia, Sliding,Hiatal Hernias,Hiatal Hernias, Paraesophageal,Hiatal Hernias, Sliding,Hiatus Hernia,Hiatus Hernias,Paraesophageal Hernia,Paraesophageal Hernias,Paraesophageal Hiatal Hernias,Sliding Esophageal Hernias,Sliding Hiatal Hernias
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia