The osmotic gradient in kidney medulla: a retold story. 2002

S Kurbel, and K Dodig, and R Radić
Department of Physiology, Osijek Medical Faculty, 31000 Osijek, Croatia. sven.kurbel@public.srce.hr

This article is an attempt to simplify lecturing about the osmotic gradient in the kidney medulla. In the model presented, the kidneys are described as a limited space with a positive interstitial hydrostatic pressure. Traffic of water, sodium, and urea is described in levels (or horizons) of different osmolarity, governed by osmotic forces and positive interstitial pressure. In this way, actions of the countercurrent multiplier in nephron tubules and of the countercurrent exchanger in vasa recta are integrated in each horizon. We hope that this approach can help students to better accept conventional presentations in their textbooks.

UI MeSH Term Description Entries
D007679 Kidney Medulla The internal portion of the kidney, consisting of striated conical masses, the renal pyramids, whose bases are adjacent to the cortex and whose apices form prominent papillae projecting into the lumen of the minor calyces. Kidney Papilla,Kidney Medullas,Kidney Papillas,Medulla, Kidney,Medullas, Kidney,Papilla, Kidney,Papillas, Kidney
D009995 Osmosis Tendency of fluids (e.g., water) to move from the less concentrated to the more concentrated side of a semipermeable membrane. Osmoses
D010827 Physiology The biological science concerned with the life-supporting properties, functions, and processes of living organisms or their parts.
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013663 Teaching A formal and organized process of transmitting knowledge to a person or group. Teaching Method,Training Activity,Training Technique,Academic Training,Educational Technics,Educational Techniques,Pedagogy,Teaching Methods,Technics, Educational,Techniques, Educational,Training Activities,Training Technics,Training Techniques,Activities, Training,Activity, Training,Educational Technic,Educational Technique,Method, Teaching,Methods, Teaching,Pedagogies,Technic, Educational,Technic, Training,Technics, Training,Technique, Educational,Technique, Training,Techniques, Training,Training Technic,Training, Academic

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