Are anti-BP180 IgG1 or IgG4 autoantibodies pathogenic? 2002

Zhi Liu
Departments of Dermatology, Microbiology and Immunology, University of North Carolina, Chapel Hill, USA.

UI MeSH Term Description Entries
D007074 Immunoglobulin G The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B. Gamma Globulin, 7S,IgG,IgG Antibody,Allerglobuline,IgG(T),IgG1,IgG2,IgG2A,IgG2B,IgG3,IgG4,Immunoglobulin GT,Polyglobin,7S Gamma Globulin,Antibody, IgG,GT, Immunoglobulin
D010391 Pemphigoid, Bullous A chronic and relatively benign subepidermal blistering disease usually of the elderly and without histopathologic acantholysis. Pemphigoid,Bullous Pemphigoid,Pemphigoids
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000097805 Collagen Type XVII A 220 kDa non-fibrillar collagen and basement membrane component. It is involved in healing wounds of the EPITHELIUM, CORNEAL. 180 kDa Bullous Pemphigoid Autoantigen,BP180 Antigen,BP180 Autoantigen,Bullous Pemphigoid Autoantigen, BP180,Collagen Alpha-1(XVII) Chain,Collagen XVII,Collagen, Type XVII, Alpha 1 Chain,Type XVII Collagen
D001323 Autoantibodies Antibodies that react with self-antigens (AUTOANTIGENS) of the organism that produced them. Autoantibody
D001324 Autoantigens Endogenous tissue constituents with the ability to interact with AUTOANTIBODIES and cause an immune response. Autoantigen,Autologous Antigen,Autologous Antigens,Self-Antigen,Self-Antigens,Antigen, Autologous,Antigens, Autologous,Self Antigen,Self Antigens
D024041 Non-Fibrillar Collagens A family of structurally-related short-chain collagens that do not form large fibril bundles. Short-Chain Collagens,Nonfibrillar Collagens,Collagens, Non-Fibrillar,Collagens, Nonfibrillar,Collagens, Short-Chain,Non Fibrillar Collagens,Short Chain Collagens
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