Biomaterial Database

[Effects of periodontitis and opsonized zymosan on chemiluminescence of blood neutrophils]. 2002

Gediminas Zekonis, and Egle Ivanauskiene

Kauno medicinos universiteto Ortopedines stomatologijos klinika, Sukileliu 51, 3007 Kaunas. zekonisg@hotmail.com

The objective of the present investigation was to explore oxidative function of parodontitis patient's blood neutrophils stimulated with opsonized zymosan by method of luminol- and lucigenin-dependent chemiluminescence. The leukocytes for this study were obtained from peripheral venous blood of 16 parodontitis patients and 10 healthy subjects. The luminol-dependent chemiluminescence of stimulated neutrophils of parodontitis patients did not differ (p > 0.05) from control subjects (66,849 +/- 6372 cpm and 61,243 +/- 5240 cpm, respectively). Lucigenin-dependent chemiluminescence of stimulated neutrophils of parodontitis patients was increased (p < or = 0.001) comparing with control subjects (1361 +/- 169 cpm and 492 +/- 56 cpm respectively). The luminol- and lucigenin-dependent chemiluminescence (381 +/- 63 cpm, and 389 +/- 52 cpm, respectively) of nonstimulated neutrophils of parodontitis patients was significantly higher (p < or = 0.001) than analogous Cl (134 +/- 22 cpm and 138 +/- 16 cpm respectively) of control subjects. The results indicate that increased oxidative function of neutrophils of parodontitis patients possibly can affect parodontal health.

UI	MeSH Term	Description	Entries
D008163	Luminescent Measurements	Techniques used for determining the values of photometric parameters of light resulting from LUMINESCENCE.	Bioluminescence Measurements,Bioluminescent Assays,Bioluminescent Measurements,Chemiluminescence Measurements,Chemiluminescent Assays,Chemiluminescent Measurements,Chemoluminescence Measurements,Luminescence Measurements,Luminescent Assays,Luminescent Techniques,Phosphorescence Measurements,Phosphorescent Assays,Phosphorescent Measurements,Assay, Bioluminescent,Assay, Chemiluminescent,Assay, Luminescent,Assay, Phosphorescent,Assays, Bioluminescent,Assays, Chemiluminescent,Assays, Luminescent,Assays, Phosphorescent,Bioluminescence Measurement,Bioluminescent Assay,Bioluminescent Measurement,Chemiluminescence Measurement,Chemiluminescent Assay,Chemiluminescent Measurement,Chemoluminescence Measurement,Luminescence Measurement,Luminescent Assay,Luminescent Measurement,Luminescent Technique,Measurement, Bioluminescence,Measurement, Bioluminescent,Measurement, Chemiluminescence,Measurement, Chemiluminescent,Measurement, Chemoluminescence,Measurement, Luminescence,Measurement, Luminescent,Measurement, Phosphorescence,Measurement, Phosphorescent,Measurements, Bioluminescence,Measurements, Bioluminescent,Measurements, Chemiluminescence,Measurements, Chemiluminescent,Measurements, Chemoluminescence,Measurements, Luminescence,Measurements, Luminescent,Measurements, Phosphorescence,Measurements, Phosphorescent,Phosphorescence Measurement,Phosphorescent Assay,Phosphorescent Measurement,Technique, Luminescent,Techniques, Luminescent
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D008954	Models, Biological	Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment.	Biological Model,Biological Models,Model, Biological,Models, Biologic,Biologic Model,Biologic Models,Model, Biologic
D009504	Neutrophils	Granular leukocytes having a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.	LE Cells,Leukocytes, Polymorphonuclear,Polymorphonuclear Leukocytes,Polymorphonuclear Neutrophils,Neutrophil Band Cells,Band Cell, Neutrophil,Cell, LE,LE Cell,Leukocyte, Polymorphonuclear,Neutrophil,Neutrophil Band Cell,Neutrophil, Polymorphonuclear,Polymorphonuclear Leukocyte,Polymorphonuclear Neutrophil
D009895	Opsonin Proteins	Proteins that bind to particles and cells to increase susceptibility to PHAGOCYTOSIS, especially ANTIBODIES bound to EPITOPES that attach to FC RECEPTORS. COMPLEMENT C3B may also participate.	Opsonin,Opsonin Protein,Opsonins,Protein, Opsonin
D010518	Periodontitis	Inflammation and loss of connective tissues supporting or surrounding the teeth. This may involve any part of the PERIODONTIUM. Periodontitis is currently classified by disease progression (CHRONIC PERIODONTITIS; AGGRESSIVE PERIODONTITIS) instead of age of onset. (From 1999 International Workshop for a Classification of Periodontal Diseases and Conditions, American Academy of Periodontology)	Pericementitis,Pericementitides,Periodontitides
D010520	Aggressive Periodontitis	Inflammation and loss of PERIODONTIUM that is characterized by rapid attachment loss and bone destruction in the presence of little local factors such as DENTAL PLAQUE and DENTAL CALCULUS. This highly destructive form of periodontitis often occurs in young people and was called early-onset periodontitis, but this disease also appears in old people.	Periodontitis, Juvenile,Periodontitis, Prepubertal,Periodontosis,Early-Onset Periodontitis,Juvenile Periodontitis,Periodontitis, Aggressive, 1,Periodontitis, Circumpubertal,Prepubertal Periodontitis,Circumpubertal Periodontitis,Early Onset Periodontitis,Early-Onset Periodontitides,Juvenile Periodontitides,Periodontitides, Early-Onset,Periodontitides, Juvenile,Periodontitis, Aggressive,Periodontitis, Early-Onset,Periodontoses
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man